31 December 2024
Clamping Pol ε to the leading strand
Noopur Singh & Erik Johansson
Nature Structural & Molecular Biology volume 31, pages 1644–1645 (2024)
In vivo DNA replication dynamics unveil aging-dependent replication stress
Giacomo G. Rossetti, Noe ̈ lle Dommann, Angeliki Karamichali, Vasilis S. Dionellis, Ainhoa Asensio Aldave, Tural Yarahmadov, Eddie Rodriguez-Carballo, Adrian Keogh, Daniel Candinas, Deborah Stroka and Thanos D. Halazonetis
Cell 187,6220–6234 2024
Assembly and activation of replicative helicases at origin DNA for replication initiation
Qiongdan Zhang, Wai Hei Lam, Yuanliang Zhai
Current Opinion in Structural BiologyVolume 88 102876 2024
A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome
Ottavia Olson, Simone Pelliciari, Emma D Heron, and Tom D Deegan
EMBO J 43: 3846 - 3875 (2024)
Replication licensing regulated by a short linear motif within an intrinsically disordered region of origin recognition complex
Yue Wu, Qiongdan Zhang, Yuhan Lin, Wai Hei Lam & Yuanliang Zhai
Nature Communications volume 15, Article number: 8039 (2024)
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication
Hannah L. Mackay, Helen R. Stone, George E. Ronson, Katherine Ellis, Alexander Lanz, Yara Aghabi, Alexandra K. Walker, Katarzyna Starowicz, Alexander J. Garvin, Patrick Van Eijk, Stefan A. Koestler, Elizabeth J. Anthony, Ann Liza Piberger, Anoop S. Chauhan, Poppy Conway-Thomas, Alina Vaitsiankova, Sobana Vijayendran, James F. Beesley, Eva Petermann, Eric J. Brown, Ruth M. Densham, Simon H. Reed, Felix Dobbs, Marco Saponaro & Joanna R. Morris
Nature Communications volume 15, Article number: 8102 (2024)
Timely lagging strand maturation relies on Ubp10 deubiquitylase-mediated PCNA dissociation from replicating chromatin
Javier Zamarreño, Sofía Muñoz, Esmeralda Alonso-Rodríguez, Macarena Alcalá, Sergio Rodríguez, Rodrigo Bermejo, María P. Sacristán & Avelino Bueno
Nature Communications volume 15, Article number: 8183 (2024)
Structures of the human leading strand Polε–PCNA holoenzyme
Qing He, Feng Wang, Nina Y. Yao, Michael E. O’Donnell & Huilin Li
Nature Communications volume 15, Article number: 7847 (2024)
Pioneer factors for DNA replication initiation in metazoans
Yue Wang, Jing Liang
Volume46,2400002 2024
MCM2-7 loading-dependent ORC release ensures genome-wide origin licensing
L. Maximilian Reuter, Sanjay P. Khadayate, Audrey Mossler, Korbinian Liebl, Sarah V. Faull, Mohammad M. Karimi & Christian Speck
Nature Communications volume 15, Article number: 7306 (2024)
Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10
Yujing Ouyang, Amani Al-Amodi, Muhammad Tehseen, Lubna Alhudhali, Afnan Shirbini, Masateru Takahashi, Vlad-Stefan Raducanu, Gang Yi, Ammar Usman Danazumi, Alfredo De Biasio, Samir M Hamdan
Nucleic Acids Research, Volume 52 Pages 8880–8896 2024
Embryonic genome instability upon DNA replication timing program emergence
Saori Takahashi, Hirohisa Kyogoku, Takuya Hayakawa, Hisashi Miura, Asami Oji, Yoshiko Kondo, Shin-ichiro Takebayashi, Tomoya S. Kitajima & Ichiro Hiratani
Nature volume 633, pages 686–694 (2024)
A high-throughput screening identifies MCM chromatin loading inhibitors targeting cells with increased replication origins
Lucia Falbo, Herve ́ Te ́ cher, Vincenzo Sannino, Michela Robusto, Giovanni Faga, Federica Pezzimenti, Francesco Romeo, Luca Gabriele Colombo, Stefania Vultaggio, Daniele Fancelli, Silvia Monzani, Valentina Cecatiello, Sebastiano Pasqualato, Mario Varasi, Ciro Mercurio and Vincenzo Costanzo
iScience 27, 110567 2024
Unwinding of a eukaryotic origin of replication visualized by cryo-EM
Sarah S. Henrikus, Marta H. Gross, Oliver Willhoft, Thomas Pühringer, Jacob S. Lewis, Allison W. McClure, Julia F. Greiwe, Giacomo Palm, Andrea Nans, John F. X. Diffley & Alessandro Costa
Nature Structural & Molecular Biology volume 31, pages 1265–1276 (2024)
SUMO protease and proteasome recruitment at the nuclear periphery differently affect replication dynamics at arrested forks
Kamila Schirmeisen, Karel Naiman, Karine Fréon, Laetitia Besse, Shrena Chakraborty, Anissia Ait Saada, Antony M Carr, Karol Kramarz, Sarah A E Lambert
Nucleic Acids Research, Volume 52 Pages 8286–8302 2024
Origin recognition complex 6 overexpression promotes growth of glioma cells
Wen-lei Yang, Wei-feng Zhang, Yin Wang, Yue Lou, Yu Cai & Jun Zhu
Cell Death & Disease volume 15, Article number: 485 (2024)
Sex-specific DNA-replication in the early mammalian embryo
Jason Alexander Halliwell, Javier Martin-Gonzalez, Adnan Hashim, John Arne Dahl, Eva R. Hoffmann & Mads Lerdrup
Nature Communications volume 15, Article number: 6323 (2024)
Single-molecule imaging reveals the mechanism of bidirectional replication initiation in metazoa
Riki Terui1∙ Scott E. Berger∙ Larissa A. Sambel1∙ Dan Song∙ Gheorghe Chistol
Cell Volume 187, Issue 15P3992-4009, 2024
DNA polymerase κ participates in early S-phase DNA replication in human cells
Feng Tang, Yinan Wang, Ting Zhao, Jun Yuan, Andrew H. Kellum Jr, and Yinsheng Wang
PNAS 121 (28) e2405473121 2024
Activity of DNA polymerase κ across the genome in human fibroblasts
Mariela C. Torres, Abbey Rebok, Dongxiao Sun, and Thomas E. Spratt https://
PNAS 121 (28) e2403130121 2024
Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution
Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert E. Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan & Nnennaya Kanu
Nature Communications volume 15, Article number: 6039 (2024)
Control of DNA replication in vitro using a reversible replication barrier
Emma J. Vontalge, Tamar Kavlashvili, Steven N. Dahmen, Matthew T. Cranford & James M. Dewar
Nature Protocols volume 19, pages 1940–1983 (2024)
MCM8 interacts with DDX5 to promote R-loop resolution
Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi-Jiang Chen, Shidou Zhao, Yajuan Yang, and Yingying Qin
EMBO J 43: 3044 - 3071 (2024)
Quantifying DNA replication speeds in single cells by scEdU-seq
Jeroen van den Berg, Vincent van Batenburg, Christoph Geisenberger, Rinskje B. Tjeerdsma
Anchel de Jaime-Soguero, Sergio P. Acebrón, Marcel A. T. M. van Vugt & Alexander van Oudenaarden
Nature Methods | Volume 21 1175–1184 2024
The loss of DNA polymerase epsilon accessory subunits POLE3–POLE4 leads to BRCA1-independent PARP inhibitor sensitivity
Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, Eva Pinto Jurado, Siham Zentout, Alexandra Mihuţ, Anna Georgina Kopasz, Mihály Mérey, Rebecca Smith, Abhishek Bharadwaj Sharma, Nicholas D Lakin, Andrew James Bowman, Lajos Haracska, Sébastien Huet, Gyula Timinszky
Nucleic Acids Research, Volume 52 Pages 6994–7011 2024
Mapping fast DNA polymerase exchange during replication
Longfu Xu, Matthew T. J. Halma & Gijs J. L. Wuite
Nature Communications volume 15, Article number: 5328 (2024)
DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility
Shuangyi Xu, Ning Wang, Michael V. Zuccaro, Jeannine Gerhardt, Rajan Iyyappan, Giovanna Nascimento Scatolin, Zongliang Jiang, Timour Baslan, Amnon Koren & Dieter Egli
Nature Communications volume 15, Article number: 5247 (2024)
Phosphorylation of Orc6 During Mitosis Regulates DNA Replication and Ribosome Biogenesis
Fredy Kurniawana , Arindam Chakraborty, Humayra Z. Oishi, Minxue Liu, Mariam K. Arif, David Chen,
Molecular and Cellular Biology Volume 44 Pages 289-301 2024
Replication protein A dynamically re-organizes on primer/template junctions to permit DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis
Jessica L Norris, Lindsey O Rogers, Kara G Pytko, Rachel L Dannenberg, Samuel Perreault, Vikas Kaushik, Sahiti Kuppa, Edwin Antony, Mark Hedglin
Nucleic Acids Research, Volume 52 Pages 7650–7664 2024
CryoEM insights into RNA primer synthesis by the human primosome
Zhan Yin, Mairi L. Kilkenny, De-Sheng Ker, Luca Pellegrini
Febs J Volume291 Pages 1813-1829 2024
Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
Bethany Rebekah Hill, Meryem Ozgencil, Lauryn Buckley-Benbow, Sophie Louise Pamela Skingsley,
Danielle Tomlinson, Carmen Ortueta Eizmendi, Alessandro Agnarelli,and Roberto Bellelli
Cell Reports 43, 114205, 2024
Improved detection of DNA replication fork-associated proteins
Rebecca S. Rivard,Ya-Chu Chang, Ryan L. Ragland, Yee-Mon Thu, Muzaffer Kassab,
Rahul Shubhra Mandal, Susan K. Van Riper, Katarzyna Kulej, LeeAnn Higgins, Todd M. Markowski, David Shang, Jack Hedberg, Luke Erber, Benjamin Garcia, Yue Chen, Anja-Katrin Bielinsky and Eric J. Brown
Cell Reports 43, 114178 2024
S-phase checkpoint prevents leading strand degradation from strand-associated nicks at stalled replication forks
Alberto Bugallo, Mar Sánchez, María Fernández-García, Mónica Segurado
Nucleic Acids Research, Volume 52 Pages 5121–5137 2024
DNA polymerase delta governs parental histone transfer to DNA replication lagging strand
Congcong Tian, Qin Zhang, Jing Jia, +18 , and Haiyun Gan
PNAS 121 (20) e2400610121 2024
The origin recognition complex requires chromatin tethering by a hypervariable intrinsically disordered region that is functionally conserved from sponge to man
Olubu A Adiji, Brendan S McConnell, Matthew W Parker
Nucleic Acids Research, Volume 52 Pages 4344–4360 2024
Mechanism of DNA unwinding by MCM8-9 in complex with HROB
Ananya Acharya, Hélène Bret, Jen-Wei Huang, Martin Mütze, Martin Göse, Vera Maria Kissling, Ralf Seidel, Alberto Ciccia, Raphaël Guérois & Petr Cejka
Nature Communications volume 15, Article number: 3584 (2024)
Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication
Jacob T. Landeck ∙ Joshua Pajak ∙ Emily K. Norman ∙ Emma L. Sedivy ∙ Brian A. Kelch
JBC Volume 300, Issue 4107166 2024
A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
Patricia Ubieto-Capella, Pilar Ximénez-Embún, Daniel Giménez-Llorente, Ana Losada, Javier Muñoz, Juan Méndez
Cell Reports Volume 43, Issue 4114024 2024
The functional significance of the RPA- and PCNA-dependent recruitment of Pif1 to DNA
Oleksii Kotenko and Svetlana Makovets
EMBO Rep 25: 1734 - 1751(2024)
The ORFIUS complex regulates ORC2 localization at replication origins
Zelei Yang, Saie Mogre, Ruiyang He, Emma L Berdan, Shannan J Ho Sui, Sarah J Hill
NAR Cancer, Volume 6 zcae003
Ordered and disordered regions of the Origin Recognition Complex direct differential in vivo binding at distinct motif sequences
Michal Chappleboim, Segev Naveh-Tassa, Miri Carmi, Yaakov Levy, Naama Barkai
Nucleic Acids Research, Volume 52 Pages 5720–5731 2024
PrimPol Variant V102A with Altered Primase and Polymerase Activities
Elizaveta O. Boldinova, Andrey G. Baranovskiy, Yulia V. Filina, Regina R. Miftakhova, Yana F. Shamsutdinova, Tahir H. Tahirov, Alena V. Makarova
Journal of Molecular Biology Volume 436 168542 2024
Parental histone transfer caught at the replication fork
Ningning Li, Yuan Gao, Yujie Zhang, Daqi Yu, Jianwei Lin, Jianxun Feng, Jian Li, Zhichun Xu, Yingyi Zhang, Shangyu Dang, Keda Zhou, Yang Liu, Xiang David Li, Bik Kwoon Tye, Qing Li, Ning Gao & Yuanliang Zhai
Nature volume 627, pages 890–897 (2024)
RTF2 controls replication repriming and ribonucleotide excision at the replisome
Brooke A. Conti, Penelope D. Ruiz, Cayla Broton, Nicolas J. Blobel, Molly C. Kottemann, Sunandini Sridhar, Francis P. Lach, Tom F. Wiley, Nanda K. Sasi, Thomas Carroll & Agata Smogorzewska
Nature Communications volume 15, Article number: 1943 (2024)
CST–polymerase α-primase solves a second telomere end-replication problem
Hiroyuki Takai, Valentina Aria, Pamela Borges, Joseph T. P. Yeeles & Titia de Lange
Nature volume 627, pages 664–670 (2024)
TopBP1 utilises a bipartite GINS binding mode to support genome replication
Matthew Day, Bilal Tetik, Milena Parlak, Yasser Almeida-Hernández, Markus Räschle, Farnusch Kaschani, Heike Siegert, Anika Marko, Elsa Sanchez-Garcia, Markus Kaiser, Isabel A. Barker, Laurence H. Pearl, Antony W. Oliver & Dominik Boos
Nature Communications volume 15, Article number: 1797 (2024)
The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopus egg extracts
Yoshitaka Kawasoe, Sakiko Shimokawa, Peter J. Gillespie, J. Julian Blow, Toshiki Tsurimoto1, Tatsuro S. Takahashi
JBC Volume 300, Issue 1105588 2024
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway
Ming Tang, Shasha Yin, Hongliang Zeng, Ao Huang, Yujia Huang, Zhiyi Hu, Ab Rauf Shah, Shuyong Zhang, Haisen Li & Guofang Chen
Cell Death & Disease volume 15, Article number: 69 (2024)
The genetic landscape of origins of replication in P. falciparum
Casilda Muñoz Castellano, Laurent Lacroix, Emilie Mathis, Paulina Prorok, Magali Hennion, Jose-Juan Lopez-Rubio, Marcel Méchali, Ana Rita Gomes
Nucleic Acids Research, Volume 52 Pages 660–676 2024
Coordination of cohesin and DNA replication observed with purified proteins
asuto Murayama, Shizuko Endo, Yumiko Kurokawa, Ayako Kurita, Sanae Iwasaki & Hiroyuki Araki
Nature volume 626, pages 653–660 (2024)
DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors
Daria Ostroverkhova,Kathrin Tyryshkin, Annette K. Beach, Elizabeth A. Moore, Yosef Masoudi-Sobhanzadeh, Stephanie R. Barbari, Igor B. Rogozin, Konstantin V. Shaitan, Anna R. Panchenko,and Polina V. Shcherbakova
Cell Reports 43, 113655 2024
Incomplete reprogramming of DNA replication timing in induced pluripotent stem cells
Matthew M. Edwards, Ning Wang, Dashiell J. Massey, Sakshi Bhatele, Dieter Egli,Amnon Koren
Cell reports Volume 43, Issue 1113664 2024
Template switching between the leading and lagging strands at replication forks generates inverted copy number variants through hairpin-capped extrachromosomal DNA
Rebecca Martin , Claudia Y. Espinoza , Christopher R. L. Large, Joshua Rosswork, Cole Van Bruinisse, Aaron W. Miller, Joseph C. Sanchez, Madison Miller, Samantha Paskvan, Gina M. Alvino, Maitreya J. Dunham, M. K. Raghuraman, Bonita J. Brewer
PLoS Genet 20(1): e1010850.
Specialized replication mechanisms maintain genome stability at human centromeres
Andrea Scelfo,Annapaola Angrisani,Marco Grillo, Jérôme Déjardin, Therese Wilhelm Daniele Fachinetti
Mol Cell Volume 84, Issue 6P1003-1020.E10 2024
The proofreading exonuclease of leading-strand DNA polymerase epsilon prevents replication fork collapse at broken template strands
Tasnim Ahmad, Ryotaro Kawasumi, Tomoya Taniguchi, Takuya Abe, Kazuhiro Terada, Masataka Tsuda, Naoto Shimizu, Toshiki Tsurimoto, Shunichi Takeda, Kouji Hirota
Nucleic Acids Research, Volume 51 Pages 12288–12302 2023
Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency
Anna Chanou, Matthias Weiβ, Karoline Holler, Atiqa Sajid, Tobias Straub, Jana Krietsch, Andrea Sanchi, Henning Ummethum, Clare S K Lee, Elisabeth Kruse, Manuel Trauner, Marcel Werner, Maxime Lalonde, Massimo Lopes, Antonio Scialdone, Stephan Hamperl
Nucleic Acids Research, Volume 51 Pages 12303–12324 2023
DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process
Lance D. Langston, Roxana E. Georgescu, and Michael E. O'Donnell
PNAS 120 e2316466120 2023
DONSON is required for CMG helicase assembly in the mammalian cell cycle
Cecile Evrin, Vanesa Alvarez, Johanna Ainsworth, Ryo Fujisawa, Constance Alabert, and Karim Labib
EMBO rep 24: e57677 (2023)
Disorders in the CMG helicase complex increase the proliferative capacity and delay chronological aging of budding yeast
Karolina Stępień, Adrianna Skoneczna, Monika Kula-Maximenko, Łukasz Jurczyk, Mateusz Mołoń
Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchVolume 1871 2024, 119621
RIF1 regulates early replication timing in murine B cells
Daniel Malzl, Mihaela Peycheva, Ali Rahjouei, Stefano Gnan, Kyle N. Klein, Mariia Nazarova, Ursula E. Schoeberl, David M. Gilbert, Sara C. B. Buonomo, Michela Di Virgilio, Tobias Neumann & Rushad Pavri
Nature Communications volume 14, Article number: 8049 (2023)
Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication OriginsR
Roch Tremblaya, Yosra Mehrjoo, Oumaima Ahmed, Antoine Simoneau, Mary E. McQuaid, El Bachir Affar, Corey Nislow, Guri Giaever & Hugo Wurtele
Molecular and Cellular Biology Volume 43 Pages 566-595 2023
Replication‐induced DNA secondary structures drive fork uncoupling and breakage
Sophie L Williams, Corella S Casas‐Delucchi, Federica Raguseo, Dilek Guneri, Yunxuan Li, Masashi Minamino, Emma E Fletcher, Joseph TP Yeeles, Ulrich F Keyser, Zoë AE Waller, Marco Di Antonio and Gideon Coster
EMBO J 42: e114334(2023)
The structural mechanism of dimeric DONSON in replicative helicase activation
Milos A. Cvetkovic1,Paolo Passaretti Agata Butryn Alicja Reynolds-Winczura, Georgia Kingsley, Aggeliki Skagia, Cyntia Fernandez-Cuesta, Divyasree Poovathumkadavil, Roger George, Anoop Chauhan, Satpal Jhujh, Grant S. Stewart, Agnieszka Gambus, and Alessandro Costa
Molecular Cell Volume 83 P4017-4031 2023
A sensor complements the steric gate when DNA polymerase ϵ discriminates ribonucleotides
Vimal Parkash, Yashraj Kulkarni, Göran O Bylund, Pia Osterman, Shina Caroline Lynn Kamerlin, Erik Johansson
Nucleic Acids Research, Volume 51 Pages 11225–11238 2023
Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase δ-dependent mechanism
Amr M. Al-Zain, Mattie R. Nester, Iffat Ahmed & Lorraine S. Symington
Nature Communications volume 14, Article number: 7020 (2023)
Coordination of Primer Initiation Within the Catalytic Domain of Human PrimPol
Lewis J. Bainbridge, Katerina Zabrady, Aidan J. Doherty
Journal of Molecular Biology Volume 435 168338 2023
Cooperative interaction of CST and RECQ4 resolves G‐quadruplexes and maintains telomere stability
Tingfang Li, Miaomiao Zhang, Yanjing Li, Xinyu Han, Lu Tang, Tengfei Ma, Xiaotong Zhao, Rui Zhao, Yuwen Wang, Xue Bai, Kai Zhang, Xin Geng, Lei Sui, Xuyang Feng, Qiang Zhang, Yang Zhao, Yang Liu, Jason A Stewart, and Feng Wang
EMBO rep 24: e55494 (2023)
Distinct RPA functions promote eukaryotic DNA replication initiation and elongation
Alexandra M Pike, Caitlin M Friend, Stephen P Bell
Nucleic Acids Research, Volume 51,Pages 10506–10518 2023
Flexibility and Distributive Synthesis Regulate RNA Priming and Handoff in Human DNA Polymerase α-Primase
John J. Cordoba, Elwood A. Mullins, Lauren E. Salay, Brandt F. Eichman, Walter J. Chazin
Journal of Molecular Biology Volume 435 168330 2023
Freedom to err: The expanding cellular functions of translesion DNA polymerases
Ines Paniagua and Jacqueline J.L. Jacobs
Molecular Cell 83 3608 2023
Review Completing genome replication outside of S phase
Rahul Bhowmick, Ian D. Hickson, and Ying Liu
Molecular Cell 83 3596 2023
DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation
Function and mechanism of MCM8 in the development and progression of colorectal cancer
Shaojun Yu, Weixing Dai, Senlin Zhao, Yongzhi Yang, Ye Xu, Jianwei Wang, Qun Deng, Jinghu He and Debing Shi
Journal of Translational Medicine (2023) 21:623
Synergism between CMG helicase and leading strand DNA polymerase at replication fork
Zhichun Xu, Jianrong Feng, Daqi Yu, Yunjing Huo, Xiaohui Ma, Wai Hei Lam, Zheng Liu, Xiang David Li, Toyotaka Ishibashi, Shangyu Dang & Yuanliang Zhai
Nature Communications volume 14, Article number: 5849 (2023)
DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans
YISUI XIA, REMI SONNEVILLE, MICHAEL JENKYN-BEDFORD, LIQIN JI, CONSTANCE ALABERT, YE HONG, JOSEPH T. P. YEELES, AND KARIM P. M. LABIB
SCIENCE Vol 381, Issue 6664
In silico protein interaction screening uncovers DONSON’s role in replication initiation
YANG LIM, LUKAS TAMAYO-ORREGO, ERNST SCHMID, ZYGIMANTE TARNAUSKAITE, OLGA V. KOCHENOVA, RHIAN GRUAR, SACHIKO MURAMATSU, LUKE LYNCH, AITANA VERDU SCHLIE,PAULA CARROLL, GEORGHE CHISTOL, MARTIN REIJNS, MASATU KANEMAKI, ANDREW JACKSON, AND JOHANNES C. WALTER
SCIENCE Vol 381, Issue 6664
Novel role of DONSON in CMG helicase assembly during vertebrate DNA replication initiation
Yoshitami Hashimoto , Kota Sadano, Nene Miyata, Haruka Ito, and Hirofumi Tanaka
EMBO J 42: e114131(2023)
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