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Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance Demis Menolfi, Axel Delamarre, Armelle Lengronne, Philippe Pasero, Dana Branze Mol cell Volume 60, Issue 6, p835–846, 17 December 2015

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Replication stress activates DNA repair synthesis in mitosis Sheroy Minocherhomji, Songmin Ying, Victoria A. Bjerregaard, Sara Bursomanno, Aiste Aleliunaite, Wei Wu, Hocine W. Mankouri, Huahao Shen, Ying Liu & Ian D. Hickson Nature 528, 286–290 (10 December 2015)

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M. Carmen Herrera, Silvia Tognetti, Alberto Riera, Juergen Zech, Pippa Clarke, Alejandra Fernández-Cid, and Christian Speck A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase Nucl. Acids Res. (02 December 2015) 43 (21): 10238-10250

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Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA Julien Gros, Charanya Kumar, Gerard Lynch, Tejas Yadav, Iestyn Whitehouse, Dirk Remus Mol cell Volume 60, Issue 5, p797–807, 3 December 2015

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DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene Ryan Griffin Thys and Yuh-Hwa Wang J. Biol. Chem. 2015; 290:28953-28962

no postings this week

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Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe Catarina A. Marques, Nicholas J. Dickens, Daniel Paape, Samantha J. Campbell and Richard McCulloch* Genome Biology (2015) 16:230

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Structural organization of human replication timing domains Rasha E. Boulos, Guénola Drillon, Françoise Argoul, Alain Arneodo, Benjamin Audit FEBS Letters Volume 589, Issue 20, Part A, 7 October 2015, Pages 2944–2957

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c-ETS transcription factors play an essential role in the licensing of human MCM4 origin of replication Kaveri Sidhu, Vijay Kumar Biochimica et Biophysica Acta 1849 (2015) 1319–1328

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Rif1 binds to G quadruplexes and suppresses replication over long distances Yutaka Kanoh, Seiji Matsumoto, Rino Fukatsu, Naoko Kakusho, Nobuaki Kono, Claire Renard-Guillet, Koji Masuda, Keisuke Iida, Kazuo Nagasawa, Katsuhiko Shirahige & Hisao Masai Nature Structural & Molecular Biology 22, 889–897 (2015)

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Polymerase δ replicates both strands after homologous recombination–dependent fork restart - Izumi Miyabe, Ken'Ichi Mizuno, Andrea Keszthelyi, Yasukazu Daigaku, Meliti Skouteri, Saed Mohebi, Thomas A Kunkel, Johanne M Murray & Antony M Carr Nature Structural & Molecular Biology 22, 932–938 (2015)

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Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing Jordan R. Becker,Carles Pons,Hai Dang Nguyen,Michael Costanzo,Charles Boone,Chad L. Myers,Anja-Katrin Bielinsky PLoS Genet 11(11): e1005659

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The Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase Irina Bruck and Daniel L. Kaplan J. Biol. Chem. 2015; 290:27414-27424

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High-Resolution Profiling of Drosophila Replication Start Sites Reveals a DNA Shape and Chromatin Signature of Metazoan Origins Federico Comoglio, Tommy Schlumpf, Virginia Schmid, Remo Rohs, Christian Beisel, and Renato Paro Cell Reports 11, 821–834