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A TRIM28–MCM7 regulatory axis sustains DNA replication programs in glioblastoma Xiaosong Hu, Li Yang, Hongjuan Cui Biochemical and Biophysical Research Communications Volume 829, 3 September 2026, 154150

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Structural and mechanistic insights into primer synthesis initiation by DNA primase Pengzhi Wu, Fred F. Damberger, Johannes Zehnder, Nina Wehr, Niklas Senning, Georg Lipps, Thomas Wiegand & Frédéric H.-T. Allain Nature Communications (2026)

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CHD1L maintains genome integrity by facilitating okazaki fragment maturation Litong Nie , Jialing Fu , Min Huang , Huimin Zhang , Tiantian Ma , Chang Yang , Siting Li , Chao Wang , Junjie Chen Nucleic Acids Research, Volume 54, Issue 12, 8 July 2026, gkag606,

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DNA-damage dependent interaction of Orc6 to SMARCA1 in S-phase modulates chromatin remodeling Dazhen Liu , Mohit Mishra , Youyang Wang , Humayra Oishi , Aneek Mirza , Iman Fatimah Mohajir , Neha Chetlangia , Jay Sonalkar , Yo-Chuen Lin , Kannanganattu V Prasanth and Supriya G Prasanth Nucleic Acids Research, Volume 54, Issue 12, 8 July 2026, gkag582,

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RECQ4 arginine methylation suppresses single-stranded DNA gap accumulation at replication forks Ning Ma , Xiaohua Xu , Michael Espinoza , Chou-Wei Chang , Yukari Shiozaki , Zhigang Guo , Louis Izuagie , Binghui Shen , Yanzhong Yang , Yilun Liu Nucleic Acids Research, Volume 54, Issue 12, 8 July 2026, gkag655,

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Replication origin firing capacity indicates ATR inhibitor sensitivity A. Lumeau, P. L. Pfuderer, J. A. Scarth, E. Maniati, M. A. Guscott, N. Shaikh, F. B. Copley, H. Gerdes, S. De Angelis, E. L. Alard, J. Wang, P. R. Cutillas, F. K. Mardakheh, M. A. Boemo, J. V. Forment & S. E. McClelland Nature Communications (2026)

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Spatial organization and dynamics of genome replication: from forks to foci Sunil K Pradhan , Maria Arroyo , Maruthi K Pabba , Heinrich Leonhardt , M Cristina Cardoso Nucleic Acids Research, Volume 54, Issue 11, 24 June 2026, gkag550,

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Distinct repair outcomes from single and convergent replication fork collapse Sara C. Conwell, Khushi V. N. Patel, Savannah J. Weeks-Pollenz, Steven N. Dahmen, Matthew T. Cranford, William G. Dunphy, David T. Long, David Cortez & James M. Dewar Nature Structural & Molecular Biology volume 33, pages 939–952 (2026)

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Structure of the pre-initiation complex explains CMGE biogenesis Thomas Pühringer, Berta Canal, Giacomo Palm, Agata Butryn, Emma C. Couves, Oliver Willhoft, Jacob S. Lewis, John F. X. Diffley & Alessandro Costa Nature (2026)

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TASP1-mediated cleavage of REV3L enhances the activity of DNA polymerase ζ in mammalian cells Jordane Goulas, Basile Guignier, Barbara Ben Yamin, Caroline Pouvelle, Andrey Yurchenko, Emmanuelle Despras, Luciana de Oliveira, Pierre Laplante, Dorian Bochaton, Damien Plassard, Wei Yang, François-Xavier Theillet, Xavier Veaute, Richard D. Wood, Sergey Nikolaev, Agnès M. Cordonnier & Patricia L. Kannouche  Nature Communications (2026)

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ATP is dispensable for E. coli DNA replication and eukaryotic helicase activity Richard R. Spinks, Aleksa Lakic, Celine Kelso, Slobodan Jergic, Olga Yurieva, Zhi-Qiang Xu, Michael E. O’Donnell, Nicholas E. Dixon, Antoine M. van Oijen, Jacob S. Lewis & Lisanne M. Spenkelink  Nat Commun (2026).

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Replication origin flexibility: a tool to mitigate the hazards of excess replication Haiqing Fu ∙ Christophe E. Redon ∙ Hannah M. Brenner ∙ Michael R. Ack ∙ Mirit I. Aladjem Trends in Genetics, 2026; 42, 510-523

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Primase subunit 2 regulates the proliferation and apoptosis of gastric cancer cells via MCM7/CDK4 and Bax/Bcl-2 pathways Biochimica et Biophysica Acta (BBA) - General Subjects Volume 1870, Issue 7, July 2026, 130947

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Regulation of DNA replication and 3D genome organization during early embryogenesis Ichiro Hiratani Current Opinion in Genetics & Development June 2026 Article: 102469 Volume: Volume 98

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An updated view on lagging strand DNA replication: implications for the replication stress response Rodrigo Martín-Rufo & Emilio Lecona Cell cycle 25 Pages 1-16 22 Mar 2026

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Deciphering the dual effects of transcription on DNA replication elongation by replication-associated Micro-C Zhengrong Zhangding ∙ Xuhao Liu ∙ Haoxin Liang ∙ Yaxu Fan ∙ Yu Peng ∙ Wanqin Rao ∙ Wanlin Chen ∙ Jiazhi Hu Molecular Cell, 2026; 86, 1870-1880.e5

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Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR Jung-Hoon Yoon, Karthi Sellamuthu, Robert E. Johnson, Louise Prakash and Satya Prakash Genes & Dev. 2026.

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Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair and replication fork protection Jeffrey N. Katz, Lorena Samentar, Qingming Fang, Jae-Hoon Ji, Wenjing Li, Qiongmei Gao, Sahiti Kuppa, Boya Gao, Cody M. Rogers, Hardeep Kaur, Aida Badamchi Shabestari, Arijit Dutta, Shahrez Syed, Miriam Tovar, Nozomi Tomimatsu, Bipasha Mukherjee, Elizabeth M. Irvin, Shuo Zhou, Amyn A. Habib, David S. Libich, Robert Hromas, Alexander V. Mazin, Manjeet K. Rao, Shaun K. Olsen, Elizabeth V. Wasmuth, Ana Losada, Daohong Zhou, Hong Wang, Li Lan, Eric C. Greene, Weixing Zhao, Youngho Kwon, Sandeep Burma & Patrick Sung  Nature Communications (2026)

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Dynamic regulation of origin firing factors links CDK activity to dormant origin activation Md Shahadat Hossain, Courtney G. Sansam, Kimberlie A. Wittig, Tyler D. Noble, Kevin A. Boyd & Christopher L. Sansam  Nature Communications (2026)

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Visualization of the complete preprimosome reveals the structural mechanisms governing DNA replication restart Peter L. Ducos, Alexander T. Duckworth, Kenneth A. Satyshur, James L. Keck & Timothy Grant Nature Communications (2026)

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Distinct roles of MCM2-7 subunits in replication licensing in human cells Xinyu Fan, Wai Hei Lam, Daqi Yu, Huadong Jiang, Yan Chit Hui, Qiongdan Zhang, Weiran Li, Jian Li, Ziyang Lin, Zhan Yin, Wenxiong Wu, Yingyi Zhang, Nan Liu, Masato T. Kanemaki, Shangyu Dang & Yuanliang Zhai  Nature Communications

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Topological stress regulates replication fork dynamics in unperturbed S phase Deepika Jayaprakash, Josie Gannon Patterson, Ruthie Mulvaney, Quinn Dickinson, Courtney Lovejoy, Mads Lerdrup, Juan Carlos Rivera-Mulia, David Cortez & Rahul Bhowmick  Nature Communications (2026)

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ATM lifts the cGAS handbrake on DNA replication. Lin, YL., Pasero, P. Nat Cell Biol 28, 842–843 (2026).

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ATM counteracts chromatin-bound cGAS during DNA replication Yunhao Song, Xiaojuan Ran, Yu Xu, Kartik Subramanian, Chao Dai, Mavrakis Konstantinos, Li Lan, Vipin Yadav & Lee Zou  Nature Cell Biology volume 28, pages 946–956 (2026)

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Proximal proteomics analysis reveals DNA polymerase δ subunit 3 is a new MCM2 binding partner and promotes parental histones inheritance in mammalian cells Yaping Sun, Xiaoyan Liang, Fang Liu, Wenjuan Zhao, Jiaqi Zhou, Yue Li, Yuan Yao, Ziwei Zhang, Gang Li, Kuiming Chan, Daoqin Zhang, Zhiquan Wang, Yuan Gao, Chuanhe Yu, Yuchun Wu, Xing Kang, Lingyu Qiu, Nan Li & Haiyun Gan Cell Death & Differentiation volume  33, pages 1050–1064 (2026)

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A thumb-domain insertion balances processivity and fidelity in DNA polymerase ε Noopur Singh , Göran O Bylund , Erik Johansson Nucleic Acids Research, Volume 54, Issue 6, 13 April 2026, gkag282,

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Slx4 and Fun30/SMARCAD1 coordinate S-phase checkpoint regulation and replication fork protection in response to Top1–DNA crosslinks Mathilde Courtes , Thierry Boissière , Antoine Barthe , Philippe Pasero , Benjamin Pardo Nucleic Acids Research, Volume 54, Issue 7, 24 April 2026, gkag295,

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ATR and TopBP1 oppose to control dormant origin activity and global replication dynamics, providing a first defense against replication stress Stéphane Koundrioukoff , Nathan Alary , Su-Jung Kim , Thibault Collin , Antoine Toffano , Rodrigo Melendez-Garcia , Xia Wu , Yaqun Liu , Stefano Gnan , Sami El-Hilali, Olivier Brison , Filippo Rosselli , Chun-Long Chen , Michelle Debatisse Nucleic Acids Research, Volume 54, Issue 7, 24 April 2026, gkag315,

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Archaeal family B DNA polymerase facilitates lagging strand DNA replication in the Thermococcales Geraldy Lie Stefanus Liman , Marina D Black , Vladimir Potapov , Brett W Burkhart , Katherine Levine , Brenda Baker , Jaylin L Mandley , Sarah C Davidson , Andrew F Gardner , Thomas J Santangelo , Kelly M Zatopek Nucleic Acids Research, Volume 54, Issue 8, 8 May 2026, gkag395,

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Transcription at an inducible common fragile site reveals replication origin strength hierarchy Juliette Mandelbrojt , Caroline Tonnerre-Doncarli , Théo Baret , Aurélie Masson , Michelle Debatisse , Marie-Noëlle Prioleau Nucleic Acids Research, Volume 54, Issue 6, 13 April 2026, gkag297,

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Transcription elongation can be sufficient, but is not necessary, to advance replication timing. Athanasios E Vouzas, Takayo Sasaki, Juan Carlos Rivera-Mulia, Jesse L Turner, Amber N Brown, Karen E Alexander, Laura Brueckner, Bas van Steensel & David M Gilbert EMBO Rep 27, 1964–1999 (2026).

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An updated view on lagging strand DNA replication: implications for the replication stress response Rodrigo Martín-Rufo and Emilio Lecona Cell Cycle, 25(1), 1–16.

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BRCA2-dependent maturation of nascent strands during DNA replication Larissa Milano ∙ Sophie Wells ∙ Alina Vaitsiankova ∙ Lylah Drummond-Clarke ∙ Xiaoxuan Zhu ∙ Aura Carreira ∙ Masato T. Kanemaki ∙ Keith W. Caldecott Molecular Cell, 2026; 86, 1427-1440.e5

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Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication. Paula Armina V Buco, Wilson Castillo-Tandazo, Alistair M Chalk, Courtney Pilcher, Jessica K Holien, Jörg Heierhorst, Tiong Y Tan, Amnon Koren, Monique F Smeets & Carl R Walkley EMBO Rep 27, 1759–1788 (2026).