14 August 2020

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RIF1 controls replication initiation and homologous recombination repair in a radiation dose-dependent manner Yuichiro Saito, Junya Kobayashi, Masato T. Kanemaki, Kenshi Komatsu Journal of Cell Science 2020 133 https://jcs.biologists.org/content/133/12/jcs240036?rss=1

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Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome Zuanning Yuan, Roxana Georgescu, Grant D. Schauer, Michael E. O’Donnell & Huilin Li NATURE COMMUNICATIONS | (2020)11:3156 https://www.nature.com/articles/s41467-020-16910-5.pdf

22 June 2020

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status Karl P. Hodel, Meijuan J.S. Sun, Nathan Ungerleider, Hua Lu, James B. McLachlan, Zachary F. Pursell Mol Cell VOLUME 78, ISSUE 6, P1166-1177.E6

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Histone acetyltransferase 1 is required for DNA replication fork function and stability Paula A. Agudelo Garcia1, Callie M. Lovejoy, Prabakaran Nagarajan, Dongju Park, Liudmila V. Popova, Michael A. Freitas and Mark R. Parthun The Journal of Biological Chemistry 295, 8363-8373.

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Mdm4 supports DNA replication in a p53-independent fashion Kai Wohlberedt, Ina Klusmann, Polina K. Derevyanko, Kester Henningsen, Josephine Ann Mun Yee Choo, Valentina Manzini, Anna Magerhans, Celeste Giansanti, Christine M. Eischen, Aart G. Jochemsen & Matthias Dobbelstein Oncogene volume 39, pages4828–4843(2020)

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Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork Domagoj Baretić, Michael Jenkyn-Bedford, Valentina Aria, Giuseppe Cannone, Mark Skehel, Joseph T.P. Yeeles Mol Cell 78, ISSUE 5, P926-940.E13,

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Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq Annie M. Sriramachandran, Giuseppe Petrosino, María Méndez-Lago, Axel J. Schäfer, Liliana S. Batista-Nascimento, Nicola Zilio,Helle D. Ulrich Mol cell VOLUME 78, ISSUE 5, P975-985.E7,

1 June 2020

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Cohesin Causes Replicative DNA Damage by Trapping DNA Topological Stress Nicola Elizabeth Minchell, Andrea Keszthelyi, Jonathan Baxter Mol cell VOLUME 78, ISSUE 4, P739-751.E8, MAY 21, 2020

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Division of Labor between PCNA Loaders in DNA Replication and Sister Chromatid Cohesion Establishment Hon Wing Liu, Céline Bouchoux, Mélanie Panarotto, Yasutaka Kakui, Harshil Patel, Frank Uhlmann Mol Cell VOLUME 78, ISSUE 4, P725-738.E4, MAY 21, 2020

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Binding-Induced Conformational Changes Involved in Sliding Clamp PCNA and DNA Polymerase DPO4 Wen-Ting Chu, Zucai Suo, Jin Wang iScience VOLUME 23, ISSUE 5, 101117, MAY 22, 2020

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DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis Xiangzhou Meng, Lei Wei, Sujan Devbhandari, Tuo Zhang, Jenny Xiang, Dirk Remus & Xiaolan Zhao Nature Communications volume 11, Article number: 2437 (2020)

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Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine Sathya Balachander, Alli L. Gombolay, Taehwan Yang, Penghao Xu, Gary Newnam, Havva Keskin, Waleed M. M. El-Sayed, Anton V. Bryksin, Sijia Tao, Nicole E. Bowen, Raymond F. Schinazi, Baek Kim, Kyung Duk Koh, Fredrik O. Vannberg & Francesca Storici Nature Communications volume 11, Article number: 2447 (2020)

18 May 2020

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DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival Aarti Yadav, Varshni Sharma , Jyoti Pal , Pallavi Gulati, Manisha Goel, Udita Chandra, Neha Bansal, Swati Saha PLoS Pathog 16(5): e1008190.

14 May 2020

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Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA Clément Madru, Ghislaine Henneke, Pierre Raia, Inès Hugonneau-Beaufet, Gérard Pehau-Arnaudet, Patrick England, Erik Lindahl, Marc Delarue, Marta Carroni & Ludovic Sauguet Nature Communications volume 11, Article number: 1591 (2020)

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Replication Fork Barriers and Topological Barriers: Progression of DNA Replication Relies on DNA Topology Ahead of Forks Jorge B. Schvartzman Pablo Hernández Dora B. Krimer Bioessays Volume 42, Issue5 May 2020 1900204