21 February 2022

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Probing the mechanisms of two exonuclease domain mutators of DNA polymerase ϵ Joseph M Dahl, Natalie Thomas, Maxwell A Tracy, Brady L Hearn, Lalith Perera, Scott R Kennedy, Alan J Herr, Thomas A Kunkel Nucleic Acids Research, Volume 50, Issue 2, 25 January 2022,

24 January 2022

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How asymmetric DNA replication achieves symmetrical fidelity Zhi-Xiong Zhou, Scott A. Lujan, Adam B. Burkholder, Jordan St. Charles, Joseph Dahl, Corinne E. Farrell, Jessica S. Williams & Thomas A. Kunkel Nature Structural & Molecular Biology volume 28, pages 1020–1028 (2021)

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Blm helicase facilitates rapid replication of repetitive DNA sequences in early Drosophila development Jolee M Ruchert, Morgan M Brady, Susan McMahan, Karly J Lacey, Leigh C Latta, Jeff Sekelsky, Eric P Stoffregen Genetics, Volume 220, Issue 1, January 2022, iyab169

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Geminin is essential for DNA re-replication in the silk gland cells of silkworms Tai-HangLiu, Xiao-Long Dong, Peng Chen, QianZhang, Xiao-LinZhou, ChengLu, Min-HuiPan Experimental Cell Research Volume 410, Issue 1, 1 January 2022, 112951

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Water skating: How polymerase sliding clamps move on DNA Huilin Li, Fengwei Zheng, Mike O’Donnell Febs JournalVolume288, Issue24 December 2021 Pages 7256-7262

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CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism Nina Y. Yao, Dan Zhang, Olga Yurieva, and Michael E. O’Donnell PNAS January 25, 2022 119 (4) e2119580119

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Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley & Alessandro Costa Nature Structural & Molecular Biology volume 29, pages 10–20 (2022)

7 December 2021

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Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites Shyam Twayana, Albino Bacolla, Angelica Barreto-Galvez, Ruth B. De-Paula, William C. Drosopoulos, Settapong T. Kosiyatrakul, Eric E. Bouhassira, John A. Tainer, Advaitha Madireddy, and Carl L. Schildkraut PNAS November 30, 2021 118 (48) e2106477118;

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The genetic architecture of DNA replication timing in human pluripotent stem cells Qiliang Ding, Matthew M. Edwards, Ning Wang, Xiang Zhu, Alexa N. Bracci, Michelle L. Hulke, Ya Hu, Yao Tong, Joyce Hsiao, Christine J. Charvet, Sulagna Ghosh, Robert E. Handsaker, Kevin Eggan, Florian T. Merkle, Jeannine Gerhardt, Dieter Egli, Andrew G. Clark & Amnon Koren Nature Communications volume 12, Article number: 6746 (2021)

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Molecular Mechanisms of the RECQ4 Pathogenic Mutations Xiaohua Xu, Chou-Wei Chang, Min Li, Chao Liu and Yilun Liu Front. Mol. Biosci., 18 November 2021

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Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila Souradip Das, Madison Caballero, Tatyana Kolesnikova, Igor Zhimulev, Amnon Koren, Jared Nordman Genetics, Volume 219, Issue 3, November 2021, iyab147,

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Error-prone, stress-induced 3′ flap–based Okazaki fragment maturation supports cell survival HAITAO SUN, ZHAONING LU, AMANPREET SINGH, YAJING ZHOU, ERIC ZHENG, MIAN ZHOU, JINHUI WANG, XIWEI WU, ZUNSONG HU, ZHAOHUI GU, JUDITH L. CAMPBELL, LI ZHENG, AND BINGHUI SHEN SCIENCE 2 Dec 2021,Vol 374, Issue 6572 pp. 1252-1258

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Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry Yoko Hayashi-Takanaka, Yuichiro Hayashi, Yasuhiro Hirano, Atsuko Miyawaki-Kuwakado, Yasuyuki Ohkawa, Chikashi Obuse, Hiroshi Kimura, Tokuko Haraguchi, Yasushi Hiraoka Nucleic Acids Research, Volume 49, Issue 21, 2 December 2021, Pages 12152–12166

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The human telomeric proteome during telomere replication Chih-Yi Gabriela Lin, Anna Christina Näger, Thomas Lunardi, Aleksandra Vančevska, Gérald Lossaint, Joachim Lingner Nucleic Acids Research, Volume 49, Issue 21, 2 December 2021, Pages 12119–12135

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Structure of a human replisome shows the organisation and interactions of a DNA replication machine Morgan L Jones, Yasemin Baris, Martin R G Taylor, Joseph T P Yeeles EMBO J (2021)40:e108819