no postings this week

publication alert

Replication Fork Progression during Re-replication Requires the DNA Damage Checkpoint and Double-Strand Break Repair Jessica L. Alexander, M. Inmaculada Barrasa, Terry L. Orr-Weaver Current biology Volume 25, Issue 12, p1654–1660, 15 June 2015

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RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin Furqan Sami , Xing Lu , Swetha Parvathaneni , Rabindra Roy , Ronald K. Gary , Sudha Sharma Biochemical Journal Jun 01, 2015, 468 (2) 227-244;

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FEN1-mediated α-segment error editing during Okazaki fragment maturation Shafat Ali, Li Zheng & Binghui Shen Cell Cycle Volume 14, Issue 12, 2015 page 1767

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Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis Faiza M Kalfalah, Elke Berg, Morten O Christensen, René M Linka, Wilhelm G Dirks, Fritz Boege & Christian Mielke Cell Cycle Volume 14, Issue 11, 2015 pages 1704-1715

no postings this week

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Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit Yoshiaki Suwa, Jianyou Gu, Andrey G. Baranovskiy, Nigar D. Babayeva, Youri I. Pavlov and Tahir H. Tahirov The Journal of Biological Chemistry, 290, 14328-14337.

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Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate Feng-Ling Tsaia, Sriram Vijayraghavana, Joseph Prinz, Heather K. MacAlpine, David M. MacAlpine and Anthony Schwacha Mol. Cell. Biol. June 2015 vol. 35 no. 12 2131-2143

no postings this week

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The Roles of Family B and D DNA Polymerases in Thermococcus Species 9°N Okazaki Fragment Maturation* Lucia Greenough, Zvi Kelman and Andrew F. Gardner The Journal of Biological Chemistry, 290, 12514-12522.

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Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin Jeannine Gerhardt, Gulfem D. Guler, Ellen Fanning Experimental Cell Research Volume 334, Issue 2, 10 June 2015, Pages 283–293

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Phosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation Xiangzi Han, Franklin Mayca Pozo, Jacob N. Wisotsky, Benlian Wang, James W. Jacobberger, and Youwei Zhang J. Biol. Chem. 2015; 290:12370-12378

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Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells Nihan Kara, Manzar Hossain, Supriya G. Prasanth, and Bruce Stillman J. Biol. Chem. 2015; 290:12355-12369

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Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis Janice Ortega, Jessie Y. Li,Sanghee Lee, Dan Tong, Liya Gu, and Guo-Min Li PNAS 112 no. 18, 5667–5672

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Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system Ruth Stucke, Néstor García-Rodríguez, Andrés Aguilera, and Ralf Erik Wellinger PNAS vol. 112 no. 18 5779–5784