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Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA Jingchuan Sun, Cecile Evrin, Stefan A Samel, Alejandra Fernández-Cid, Alberto Riera, Hironori Kawakami, Bruce Stillman, Christian Speck & Huilin Li Nature Structural & Molecular Biology 20, 944–951