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ATR and TopBP1 oppose to control dormant origin activity and global replication dynamics, providing a first defense against replication stress Stéphane Koundrioukoff , Nathan Alary , Su-Jung Kim , Thibault Collin , Antoine Toffano , Rodrigo Melendez-Garcia , Xia Wu , Yaqun Liu , Stefano Gnan , Sami El-Hilali, Olivier Brison , Filippo Rosselli , Chun-Long Chen , Michelle Debatisse Nucleic Acids Research, Volume 54, Issue 7, 24 April 2026, gkag315,