24 September 2018
publication alert
Cellular senescence induces replication stress with almost no affect on DNA replication timing
Juan Carlos Rivera-Mulia, Hélène Schwerer, Emilie Besnard, Romain Desprat, Claudia Trevilla-Garcia, Jiao Sima, Paul Bensadoun, Anissa Zouaoui, David M. Gilbert & Jean-Marc Lemaitre
Cell Cycle Volume 17, 2018 - Issue 13 Pages 1667-1681
publication alert
Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks
Shin‐ichiro Hiraga, Chandre Monerawela, Yuki Katou, Sophie Shaw, Kate RM Clark, Katsuhiko Shirahige, Anne D Donaldson
MBO reports (2018) 19, e46222
publication alert
Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments
Hongwei Liao, Fang Ji,Thomas Helleday, Songmin Ying
EMBO reports (2018) 19, e46263
publication alert
Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
Jonas Andreas Schmid, Matteo Berti, Franziska Walser, Maria Chiara Raso, Fabian Schmid, Jana Krietsch, Henriette Stoy, Katharina Zwicky, Sebastian Ursich, Raimundo Freire, Massimo Lopes, Lorenza Penengo
Mol Cell VOLUME 71, ISSUE 6, P897-910.E8, SEPTEMBER 20, 2018
publication alert
Germline DNA replication timing shapes mammalian genome composition
Yishai Yehuda Britny Blumenfeld Nina Mayorek Kirill Makedonski Oriya Vardi Leonor Cohen-Daniel Yousef Mansour Shulamit Baror-Sebban Hagit Masika Marganit Farago et al
Nucleic Acids Research, Volume 46, Issue 16, 19 September 2018, Pages 8299–8310,
21 September 2018
publication alert
Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells
Sumeet Poudel, Jianhong Yao, Michael G. Kemp and Michael Leffak
The Journal of Biological Chemistry 293, 14497-14506
4 September 2018
publication alert
Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism
Shivangi Agarwal, Kyle Paul Smith, Yizhuo Zhou, Aussie Suzuki, Richard J. McKenney, Dileep Varma
JCB September 3, 2018 Volume 217, No. 9
publication alert
Rtt105 functions as a chaperone for replication protein A to preserve genome stability
Shuqi Li, Zhiyun Xu, Jiawei Xu,Linyu Zuo, Chuanhe Yu, Pu Zheng, Haiyun Gan, Xuezheng Wang, Longtu Li, Sushma Sharma, Andrei Chabes, Di Li, Sheng Wang, Sihao Zheng, Jinbao Li, Xuefeng Chen, Yujie Sun, Dongyi Xu, Junhong Han, Kuiming Chan, Zhi Qi, Feng, Qing Li
The EMBO Journal (2018) 37, e99154
28 August 2018
publication alert
Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
Anthony Tubbs, Sriram Sridharan, Niek van Wietmarschen, Yaakov Maman, Elsa Callen, Andre Stanlie, Wei Wu, Xia Wu, Amanda Day, Nancy Wong, Mianmian Yin, Andres Canela, Haiqing Fu, Christophe Redon, Steven C. Pruitt, Yan Jaszczyszyn, Mirit I. Aladjem, Peter D. Aplan, Olivier Hyrien, André Nussenzweig
Cell VOLUME 174, ISSUE 5, P1127-1142.E19, AUGUST 23, 2018
https://www.cell.com/cell/fulltext/S0092-8674(18)30905-X
publication alert
Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes
Sara Rodriguez-Acebes, Silvana Mourón and Juan Méndez
The Journal of Biological Chemistry293, 12855-12861.
12 August 2018
publication alert
An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea
Mengmeng Sun Xu Feng Zhenzhen Liu Wenyuan Han Yun Xiang Liang Qunxin She
Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages 6697–6711
publication alert
An archaeal primase functions as a nanoscale caliper to define primer length
Jiangyu Yan, Sandro Holzer, Luca Pellegrini, and Stephen D. Bell
PNAS June 26, 2018. 115 (26) 6697-6702
publication alert
Conformational control and DNA-binding mechanism of the metazoan origin recognition complex
Franziska Bleichert, Alexander Leitner, Ruedi Aebersold, Michael R. Botchan, and James M. Berger
PNAS June 26, 2018. 115 (26) E5906-E5915
publication alert
Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks
Kathrin S Heinz Corella S Casas-Delucchi Timea Török Dusan CmarkoAlexander Rapp Ivan Raska M Cristina Cardoso
Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 6112–6128,
publication alert
Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Jithesh Kottur Deepak T Nair
Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 5875–5885,
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