24 September 2018

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Cellular senescence induces replication stress with almost no affect on DNA replication timing Juan Carlos Rivera-Mulia, Hélène Schwerer, Emilie Besnard, Romain Desprat, Claudia Trevilla-Garcia, Jiao Sima, Paul Bensadoun, Anissa Zouaoui, David M. Gilbert & Jean-Marc Lemaitre Cell Cycle Volume 17, 2018 - Issue 13 Pages 1667-1681

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Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks Shin‐ichiro Hiraga, Chandre Monerawela, Yuki Katou, Sophie Shaw, Kate RM Clark, Katsuhiko Shirahige, Anne D Donaldson MBO reports (2018) 19, e46222

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Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments Hongwei Liao, Fang Ji,Thomas Helleday, Songmin Ying EMBO reports (2018) 19, e46263

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Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase Jonas Andreas Schmid, Matteo Berti, Franziska Walser, Maria Chiara Raso, Fabian Schmid, Jana Krietsch, Henriette Stoy, Katharina Zwicky, Sebastian Ursich, Raimundo Freire, Massimo Lopes, Lorenza Penengo Mol Cell VOLUME 71, ISSUE 6, P897-910.E8, SEPTEMBER 20, 2018

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Germline DNA replication timing shapes mammalian genome composition Yishai Yehuda Britny Blumenfeld Nina Mayorek Kirill Makedonski Oriya Vardi Leonor Cohen-Daniel Yousef Mansour Shulamit Baror-Sebban Hagit Masika Marganit Farago et al Nucleic Acids Research, Volume 46, Issue 16, 19 September 2018, Pages 8299–8310,

21 September 2018

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Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells Sumeet Poudel, Jianhong Yao, Michael G. Kemp and Michael Leffak The Journal of Biological Chemistry 293, 14497-14506

4 September 2018

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Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism Shivangi Agarwal, Kyle Paul Smith, Yizhuo Zhou, Aussie Suzuki, Richard J. McKenney, Dileep Varma JCB September 3, 2018 Volume 217, No. 9

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Rtt105 functions as a chaperone for replication protein A to preserve genome stability Shuqi Li, Zhiyun Xu, Jiawei Xu,Linyu Zuo, Chuanhe Yu, Pu Zheng, Haiyun Gan, Xuezheng Wang, Longtu Li, Sushma Sharma, Andrei Chabes, Di Li, Sheng Wang, Sihao Zheng, Jinbao Li, Xuefeng Chen, Yujie Sun, Dongyi Xu, Junhong Han, Kuiming Chan, Zhi Qi, Feng, Qing Li The EMBO Journal (2018) 37, e99154

28 August 2018

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Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse Anthony Tubbs, Sriram Sridharan, Niek van Wietmarschen, Yaakov Maman, Elsa Callen, Andre Stanlie, Wei Wu, Xia Wu, Amanda Day, Nancy Wong, Mianmian Yin, Andres Canela, Haiqing Fu, Christophe Redon, Steven C. Pruitt, Yan Jaszczyszyn, Mirit I. Aladjem, Peter D. Aplan, Olivier Hyrien, André Nussenzweig Cell VOLUME 174, ISSUE 5, P1127-1142.E19, AUGUST 23, 2018 https://www.cell.com/cell/fulltext/S0092-8674(18)30905-X

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Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes Sara Rodriguez-Acebes, Silvana Mourón and Juan Méndez The Journal of Biological Chemistry293, 12855-12861.

12 August 2018

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An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea Mengmeng Sun Xu Feng Zhenzhen Liu Wenyuan Han Yun Xiang Liang Qunxin She Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages 6697–6711

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An archaeal primase functions as a nanoscale caliper to define primer length Jiangyu Yan, Sandro Holzer, Luca Pellegrini, and Stephen D. Bell PNAS June 26, 2018. 115 (26) 6697-6702

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Conformational control and DNA-binding mechanism of the metazoan origin recognition complex Franziska Bleichert, Alexander Leitner, Ruedi Aebersold, Michael R. Botchan, and James M. Berger PNAS June 26, 2018. 115 (26) E5906-E5915

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Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks Kathrin S Heinz Corella S Casas-Delucchi Timea Török Dusan CmarkoAlexander Rapp Ivan Raska M Cristina Cardoso Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 6112–6128,

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Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Jithesh Kottur Deepak T Nair Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 5875–5885,