no postings this week

Publication Alert

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase

Samra Obeida, Anna Baccaroa, Wolfram Welteb, Kay Diederichsb, and Andreas Marx

PNAS December 14, 2010 vol. 107 no. 50 21327-21331

Publication Alert

RNAi-based screening identifies the Mms22L–Nfkbil2 complex as a novel regulator of DNA replication in human cells

Wojciech Piwko, Michael H Olma, Michael Held, Julien N Bianco, Patrick G A Pedrioli1, Kay Hofmann, Philippe Pasero, Daniel W Gerlich and Matthias Pete

The EMBO Journal (2010) 29, 4210 – 4222

Publication Alert

Cohesin organizes chromatin loops at DNA replication factories

Emmanuelle Guillou, Arkaitz Ibarra, Vincent Coulon, Juan Casado-Vela, Daniel Rico, Ignacio Casa, Etienne Schwob, Ana Losada and Juan Méndez

Genes & Dev. 2010. 24: 2812-2822

Publication Alert

Sister acts: coordinating DNA replication and cohesion establishment

Rebecca Sherwood, Tatsuro S. Takahashi, and Prasad V. Jallepalli

Genes & Dev. 2010. 24: 2723-2731

Publication Alert

Activation of Cdk2/Cyclin E complexes is dependent on the origin of replication licensing factor Cdc6 in mammalian cells

Cara L. Lunn, John C. Chrivia and Joseph J. Baldassare

Cell cycle Volume 9, Issue 22 November 15, 2010 Pages 4533 - 4541

Publication Alert

Same partners, different dance: Involvement of DNA replication proteins in centrosome regulation

James Knockleby and Hoyun Lee

Cell Cycle Volume 9, Issue 22 November 15, 2010 Pages 4487 – 4491

Publication Alert

Old fashioned genetic screens give new insights to DNA replication

Bik-Kwoon Tye

Cell cycle Volume 9, Issue 23 December 1, 2010

Publication Alert

Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands

Takeo Narita, Toshiki Tsurimoto, Junpei Yamamoto, Kana Nishihara, Kaori Ogawa, Eiji Ohashi, Terry Evans, Shigenori Iwai, Shunichi Takeda, Kouji Hirota

Genes to Cells Volume 15, Issue 12, pages 1228–1239, December 2010

Publication Alert

Origin DNA melting and unwinding in DNA replication

Dahai Gaia, Y Paul Changa and Xiaojiang S Chen

Current Opinion in Structural Biology Volume 20, Issue 6, December 2010, Pages 756-762

Publication Alert

Cyclin-dependent kinase-dependent initiation of chromosomal DNA replication

Hiroyuki Araki

Current Opinion in Cell Biology Volume 22, Issue 6, December 2010, Pages 766-771

Publication Alert

Developmental Control of Late Replication and S Phase Length

Antony W. Shermoen, Mark L. McCleland, Patrick H. O'Farrell

Current Biology, Volume 20, Issue 23, 2067-2077, 11 November 2010

Publication Alert

Heterochromatin Replication: Better Late Than Ever

Tin Tin Su

Current Biology, Volume 20, Issue 23, R1018-R1020, 7 December

Publication Alert

Gene density profile reveals the marking of late replicated domains in the Drosophila melanogaster genome

Stepan N. Belyakin, Vladimir N. Babenko, Daniil A. Maksimov, Viktor V. Shloma, Evgeny Z. Kvon, Elena S. Belyaeva and Igor F. Zhimulev

CHROMOSOMA Volume 119, Number 6, 589-600

Publication Alert

Replication dynamics at common fragile site FRA6E

Elisa Palumbo, Laura Matricardi, Elena Tosoni, Aaron Bensimon and Antonella Russo

CHROMOSOMA Volume 119, Number 6, 575-587

Publication Alert

Regulation of the initiation step of DNA replication by cyclin-dependent kinases

Seiji Tanaka and Hiroyuki Araki

Chromosoma 119 / 2010

Publication Alert

Differential correction of lagging-strand replication errors made by DNA polymerases α and δ

Stephanie A. Nick McElhinnya, Grace E. Kisslingb, and Thomas A. Kunkela

PNAS December 7, 2010 vol. 107 no. 49 21070-21075

Publication Alert

Relicensing of Transcriptionally Inactivated Replication Origins in Budding Yeast

Marko Looke, Juri Reimand, Tiina Sedman, Juhan Sedman, Lari Jarvinen, Signe Varv, Kadri Peil, Kersti Kristjuhan, Jaak Vilo, and Arnold Kristjuhan

J. Biol. Chem. 2010 285: 40004-40011.

Publication Alert

Fission Yeast Swi1-Swi3 Complex Facilitates DNA Binding of Mrc1

Taku Tanaka, Mika Yokoyama, Seiji Matsumoto, Rino Fukatsu, Zhiying You, and Hisao Masai

J. Biol. Chem. 2010 285: 39609-39622.

Publication Alert

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo

Jong-Won Lim, Pamela Hummert, Jason C. Mills and Kristen L. Kroll

Development 138, 33-44.

Publication Alert

Uncoupling of Sister Replisomes during Eukaryotic DNA Replication

Hasan Yardimci, Anna B. Loveland, Satoshi Habuchi, Antoine M. van Oijen, and Johannes C. Walter

Molecular Cell, Volume 40, Issue 5, 834-840, 10 December 2010

Publication Alert

Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression

Joshua C. Black, Andrew Allen, Capucine Van Rechem, Emily Forbes, Michelle
Longworth, Katrin Tschöp, Claire Rinehart, Jonathan Quiton, Ryan Walsh, Andrea Smallwood, Nicholas J. Dyson and Johnathan R. Whetstine

Molecular Cell, Volume 40, Issue 5, 736-748, 10 December 2010

Publication Alert

Dna2 Exhibits a Unique Strand End-dependent Helicase Function

Lata Balakrishnan, Piotr Polaczek, Subhash Pokharel, Judith L. Campbell, and Robert A. Bambara

J. Biol. Chem. 2010 285: 38861-38868.

Publication Alert

Thermodynamics of Cooperative DNA Recognition at a Replication Origin and Transcription Regulatory Site

Mariano Dellarole, Ignacio E. Snchez‡, and Gonzalo de Prat Gay*

Biochemistry, 2010, 49 (48), pp 10277–10286

Publication Alert

Cell fate transitions and the replication timing decision point

David M. Gilbert

J. cell biol 191:896-897

no postings this week

Publication Alert

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase

Hyungshin Yim and Raymond L. Erikson

PNAS November 16, 2010 vol. 107 no. 46 19742-19747

Publication Alert

Stepwise loading of yeast clamp revealed by ensemble and single-molecule studies

Ravindra Kumar, Vishal C. Nashine, Padmaja P. Mishra, Stephen J. Benkovic, and Tae-Hee Lee

PNAS November 16, 2010 vol. 107 no. 46 19736-19741

Publication Alert

Interaction of the Retinoblastoma Protein with Orc1 and Its Recruitment to Human Origins of DNA Replication

Ramiro Mendoza-Maldonado, Roberta Paolinelli, Laura Galbiati, Sara Giadrossi, Mauro Giacca

PLoS ONE 5(11): e13720

Publication Alert

Transcriptional silencing functions of the yeast protein Orc1/Sir3 subfunctionalized after gene duplication

Meleah A. Hickman and Laura N. Rusche

PNAS November 9, 2010 vol. 107 no. 45 19384-19389

Publication Alert

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression

Stephanie M. Cohen, Paul D. Chastain, II, Gary B. Rosson, Beezly S. Groh, Bernard E. Weissman, David G. Kaufman, and Scott J. Bultman

Nucl. Acids Res. 2010 38: 6906-6919

Publication Alert

Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4Cdt2-Mediated PCNA-Dependent Degradation during DNA Damage

Hisanobu Oda,Michael R. Hübner,David B. Beck,Michiel Vermeulen,Jerard Hurwitz,David L. Spector,Danny Reinberg

Molecular Cell, Volume 40, Issue 3, 364-376, 28 October 2010

Publication Alert

Mec1 Is One of Multiple Kinases that Prime the Mcm2-7 Helicase for Phosphorylation by Cdc7

John C.W. Randell,Andy Fan,Clara Chan,Laura I. Francis,Ryan C. Heller,Kyriaki Galani,Stephen P. Bell

Molecular Cell, Volume 40, Issue 3, 353-363, 12 November 2010

Publication Alert

Rfc5p regulates alternate RFC complex functions in sister chromatid pairing reactions in budding yeast

Marie E. Maradeo, Anisha Garg and Robert V. Skibbens

Cell cycle Volume 9, Issue 21 November 1, 2010 Pages 4370 - 4378

Publication Alert

Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-Geminin

Philip G. Wong, Michele A. Glozak, Thinh V. Cao, Cyrus Vaziri, Edward Seto and Mark Alexandrow

Cell cycle Volume 9, Issue 21 November 1, 2010 Pages 4351 – 4363

Publication Alert

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells

Mathieu Tardat, Julien Brustel, Olivier Kirsh, Christine Lefevbre, Mary Callanan, Claude Sardet & Eric Julien

Nature Cell Biology 12 , 1086–1093 (2010)

Publication Alert

Proliferating cell nuclear antigen in the cytoplasm interacts with components of glycolysis and cancer

Stanislav N. Naryzhnya and Hoyun Lee

Febs letters Volume 584, Issue 20, 22 October 2010, Pages 4292-4298

Publication Alert

Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast

Yuanliang Zhai, Philip Y. K. Yung, Lin Huo and Chun Liang

Journal of Cell Science 123, 3933-3943 (2010)

Publication Alert

Replication Factor C Complexes Play Unique Pro- and Anti-Establishment Roles in Sister Chromatid Cohesion

Marie E. Maradeo, Robert V. Skibbens

PLoS ONE 5(10): e15381

Publication Alert

Ribonucleoprotein Particles Containing Non-Coding Y RNAs, Ro60, La and Nucleolin Are Not Required for Y RNA Function in DNA Replication

Alexander R. Langley, Helen Chambers, Christo P. Christov, Torsten Krude

PLoS ONE 5(10): e13673

Publication Alert

Proliferating Cell Nuclear Antigen (PCNA) Is Required for Cell Cycle-regulated Silent Chromatin on Replicated and Nonreplicated Genes

Andrew Miller, Jiji Chen, Taichi E. Takasuka, Jennifer L. Jacobi, Paul D. Kaufman, Joseph M. K. Irudayaraj, and Ann L. Kirchmaier

J. Biol. Chem. 2010 285: 35142-35154.

Publication Alert

Flap Endonuclease 1 Mechanism Analysis Indicates Flap Base Binding Prior to Threading

Jason W. Gloor, Lata Balakrishnan, and Robert A. Bambara

J. Biol. Chem. 2010 285: 34922-34931.

Publication Alert

Stable Interaction between the Human Proliferating Cell Nuclear Antigen Loader Complex Ctf18-Replication Factor C (RFC) and DNA Polymerase ϵ Is Mediated by the Cohesion-specific Subunits, Ctf18, Dcc1, and Ctf8

Takeshi Murakami, Ryuji Takano, Satoshi Takeo, Rina Taniguchi, Kaori Ogawa, Eiji Ohashi and Toshiki Tsurimoto

The Journal of Biological Chemistry, 285, 34608-34615.

Publication Alert

Cell Type–dependent Requirement for PIP Box–regulated Cdt1 Destruction During S Phase

Hyun O. Lee, Sima J. Zacharek, Yue Xiong and Robert J. Duronio

Vol. 21, Issue 21, 3639-3653, November 1, 2010

no postings this week

Publication Alert

Subtle Alterations in PCNA-Partner Interactions Severely Impair DNA Replication and Repair

Yearit Fridman, Niv Palgi, Daniel Dovrat, Shay Ben-Aroya, Philip Hieter, Amir Aharoni

PLoS Biol 8(10): e1000507

Publication Alert

Genome-wide model for the normal eukaryotic DNA replication fork

Andres A. Larrea, Scott A. Lujan, Stephanie A. Nick McElhinny, Piotr A. Mieczkowski, Michael A. Resnick, Dmitry A. Gordenin, and Thomas A. Kunkel

PNAS October 12, 2010 vol. 107 no. 41 17674-17679

Publication Alert

Matthew L. Bochman and Anthony Schwacha

The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'

Nucl. Acids Res. 2010 38: 6078-6088

Publication Alert

GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication

Gabriele Piergiovanni and Vincenzo Costanzo

Cell Cycle Volume 9, Issue 18 September 15, 2010 Pages 3662 – 3666

Publication Alert

Active Site Mutations in Mammalian DNA Polymerase {delta} Alter Accuracy and Replication Fork Progression

Michael W. Schmitt, Ranga N. Venkatesan, Marie-Jeanne Pillaire, Jean-Sebastien Hoffmann, Julia M. Sidorova, and Lawrence A. Loeb

J. Biol. Chem. 2010 285: 32264-32272.

Publication Alert

Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion

K-M Lau, Q K Y Chan, J C S Pang, K K W Li1, W W Yeung, N Y F Chung, P C Lui, Y-S Tam, H-M Li, L Zhou, Y Wang, Y Mao and H-K Ng

Oncogene (2010) 29, 5475–5489

Publication Alert

Drosophila Sld5 is essential for normal cell cycle progression and maintenance of genomic integrity

Catherine A. Gougea and Tim W. Christensen

Biochemical and Biophysical Research Communications Volume 400, Issue 1, 10 September 2010, Pages 145-150

Publication Alert

Molecular architecture of the DNA replication origin activation checkpoint

Slavica Tudzarova, Matthew W B Trotter, Alex Wollenschlaeger, Claire Mulvey, Jasminka Godovac-Zimmermann, Gareth H Williams and Kai Stoeber

The EMBO Journal (2010) 29, 3381 – 3394

Publication Alert

A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus

Subhradip Karmakar, Milind C Mahajan, Vincent Schulz, Gokul Boyapaty and Sherman M Weissman

The EMBO Journal (2010), 29, 3260 - 3271; 10.1038/emboj.2010.204

Publication Alert

A WD-Repeat Protein Stabilizes ORC Binding to Chromatin

Zhen Shen, Kizhakke M. Sathyan, Yijie Geng, Ruiping Zheng, Arindam Chakraborty, Brian Freeman, Fei Wang, Kannanganattu V. Prasanth, Supriya G. Prasanth

Molecular Cell, Volume 40, Issue 1, 99-111, 8 October 2010

Publication Alert

Structural Analysis of the Interactions Between Hsp70 Chaperones and the Yeast DNA Replication Protein Orc4p

María Moreno-del Álamo, Alicia Sánchez-Gorostiaga, Ana M. Serrano, Alicia Prieto, Jorge Cuéllar, Jaime Martín-Benito, José M. Valpuesta and Rafael Giraldo

Journal of Molecular Biology Volume 403, Issue 1, 15 October 2010, Pages 24-39

Publication Alert

Damage-induced phosphorylation of Sld3 is important to block late origin firing

Jaime Lopez-Mosqueda, Nancy L. Maas, Zophonias O. Jonsson, Lisa G. DeFazio-Eli, James Wohlschlegel & David P. Toczyski

Nature 467, 479-483 (23 September 2010)

Publication Alert

Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation

Philip Zegerman & John F. X. Diffley

Nature 467, 474-478 (23 September 2010)

Publication Alert

Mathematical modelling of whole chromosome replication

Alessandro P. S. de Moura, Renata Retkute, Michelle Hawkins, and Conrad A. Nieduszynski

Nucl. Acids Res. (2010) 38(17): 5623-5633

Publication Alert

Replication Factor C Recruits DNA Polymerase to Sites of Nucleotide Excision Repair but Is Not Required for PCNA Recruitment

René M. Overmeer, Audrey M. Gourdin, Ambra Giglia-Mari, Hanneke Kool, Adriaan B. Houtsmuller, Gregg Siegal, Maria I. Fousteri, Leon H. F. Mullenders, and Wim Vermeulen

Molecular and Cellular Biology, October 2010, p. 4828-4839, Vol. 30, No. 20

Publication Alert

Chk1 promotes replication fork progression by controlling replication initiation

Eva Petermanna, Mick Woodcock, and Thomas Helleday

PNAS September 14, 2010 vol. 107 no. 37 16090-16095

Publication Alert

ATP-dependent Pre-replicative Complex Assembly Is Facilitated by Adk1p in Budding Yeast

Xue Cheng, Zhen Xu, Jiafeng Wang, Yuanliang Zhai, Yongjun Lu, and Chun Liang

J. Biol. Chem. 2010 285: 29974-29980.

Publication Alert

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

Francesca Ammazzalorso, Livia Maria Pirzio, Margherita Bignami, Annapaola Franchitto and Pietro Pichierri

The EMBO Journal (2010) 29, 3156 – 3169

Publication Alert

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

Francesca Ammazzalorso, Livia Maria Pirzio, Margherita Bignami, Annapaola Franchitto and Pietro Pichierri

The EMBO Journal (2010) 29, 3156 – 3169

Publication Alert

Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication

Dongyi Xu, Parameswary Muniandy, Elisabetta Leo, Jinhu Yin, Saravanabhavan Thangavel, Xi Shen, Miki Ii, Keli Agama, Rong Guo, David Fox III, Amom Ruhikanta Meetei, Lauren Wilson, Huy Nguyen, Nan-ping Weng, Steven J Brill, Lei Li, Alessandro Vindigni, Yves Pommier, Michael Seidman and Weidong Wang

The EMBO Journal (2010) 29, 3140 – 3155

Publication Alert

Regulation of Replication Termination by Reb1 Protein-Mediated Action at a Distance

Samarendra K. Singh, Sarah Sabatinos, Susan Forsburg and Deepak Bastia

Cell, Volume 142, Issue 6, 868-878

Publication Alert

Ubc4 and Not4 Regulate Steady-State Levels of DNA Polymerase- to Promote Efficient and Accurate DNA Replication

Justin Haworth, Robert C. Alver, Melissa Anderson, and Anja-Katrin Bielinsky

Mbc Vol. 21, Issue 18, 3205-3219, September 15, 2010

Publication Alert

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2–7 complex

Lena R. Kundu, Yuji Kumata, Naoko Kakusho, Saori Watanabe, Asako Furukohri, Shou Waga, Masayuki Seki, Hisao Masai, Takemi Enomoto and Shusuke Tada

Nucleic Acids Research Volume38, Issue16 5409-5418

Publication Alert

Specific replication origins promote DNA amplification in fission yeast

Lee Kiang, Christian Heichinger, Stephen Watt, Jürg Bähler and Paul Nurse

Journal of Cell Science 123, 3047-3051 (2010)

Publication Alert

IKK and NF-κB-mediated regulation of Claspin impacts on ATR checkpoint function

Niall Steven Kenneth, Sharon Mudie and Sonia Rocha

The EMBO Journal (2010) 29, 2966 – 2978

Publication Alert

Components of the Secondary Pathway Stimulate the Primary Pathway of Eukaryotic Okazaki Fragment Processing

Ryan A. Henry, Lata Balakrishnan, Stefanie Tan Ying-Lin, Judith L. Campbell and Robert A. Bambara

Journal of Biological Chemistry, 285, 28496-28505.

Publication Alert

Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions

Sophie Gay, Anne-Marie Lachages, Gael A Millot, Sylvain Courbet, Anne Letessier, Michelle Debatisse & Olivier Brison

EMBO reports (2010) 11, 698 – 704

Publication Alert

Multiple Functions for Drosophila Mcm10 Suggested Through Analysis of Two Mcm10 Mutant Alleles

Jennifer Apger, Michael Reubens, Laura Henderson, Catherine A. Gouge, Nina Ilic, Helen H. Zhou and Tim W. Christensen

Genetics, Vol. 185, 1151-1165, August 2010

Publication Alert

Control of DNA replication: A new facet of Hox proteins?

Benoit Miotto and Yacine Graba

BioEssays Volume 32, Issue 9, pages 800–807, September 2010

Publication Alert

Pre-Steady State Kinetic Studies of the Fidelity of Nucleotide Incorporation by Yeast DNA Polymerase δ

Lynne M. Dieckman, Robert E. Johnson, Satya Prakash and M. Todd Washington

Biochemistry, 2010, 49 (34), pp 7344–7350

Publication Alert

Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage

Petra Groth, Simon Ausländer, Muntasir Mamun Majumder, Niklas Schultz, Fredrik Johansson, Eva Petermann and Thomas Helleday

Journal of Molecular Biology Volume 402, Issue 1, 10 September 2010, Pages 70-82

Publication Alert

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization

Supriya G. Prasantha, Zhen Shen, Kannanganattu V. Prasanth, and Bruce Stillman

PNAS August 24, 2010 vol. 107 no. 34 15093-15098

Publication Alert

A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA

Angela L. Groehler and Deborah A. Lannigan

JCB vol. 190 no. 4 575-586

Publication Alert

Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements

Daniele Fachinetti,Rodrigo Bermejo,Andrea Cocito,Simone Minardi,Yuki Katou,Yutaka Kanoh,Katsuhiko Shirahige,Anna Azvolinsky,Virginia A. Zakian, Marco Foiani

Molecular Cell, Volume 39, Issue 4, 595-605, 27 August 2010

Publication Alert

Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification

Brian M. Green, Kenneth J. Finn, and Joachim J. Li

Science 20 August 2010: 943-946.

Publication Alert

Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases

Yannick Jacob, Hume Stroud, Chantal LeBlanc, Suhua Feng, Luting Zhuo, Elena Caro, Christiane Hassel, Crisanto Gutierrez, Scott D. Michaels & Steven E. Jacobsen

Nature 466, 987–991 (19 August 2010)

Publication Alert

FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation

Abhishek Saharia, Daniel C. Teasley, Julien P. Duxin, Benjamin Dao, Katherine B. Chiappinelli, and Sheila A. Stewart

J. Biol. Chem. 2010 285: 27057-27066.

Publication Alert

Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange

Sarah Lambert,Ken'ichi Mizuno,Joël Blaisonneau,Sylvain Martineau,Roland Chanet,Karine Fréon,Johanne M. Murray,Antony M. Carr,Giuseppe Baldacci

Molecular Cell, Volume 39, Issue 3, 346-359, 13 August 2010

Publication Alert

Regulation of DNA Repair through DeSUMOylation and SUMOylation of Replication Protein A Complex

Hong Dou,Chao Huang,Melissa Singh,Phillip B. Carpenter,Edward T.H. Yeh

Molecular Cell, Volume 39, Issue 3, 333-345, 13 August 2010

Publication Alert

Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ϵ in the presence of replication protein A and proliferating-cell nuclear antigen

Giada A. Locatelli, Helmut Pospiech, Nicolas Tanguy Le Gac, Barbara van Loon, Ulrich Hubscher, Sinikka Parkkinen, Juhani E. Syväoja and Giuseppe Villani

Biochem. J. (2010) 429 (573–582)

Publication Alert

Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing

Oliver Bell, Michaela Schwaiger, Edward J Oakeley, Florian Lienert, Christian Beisel, Michael B Stadler & Dirk Schübeler

Nature Structural & Molecular Biology 17, 894–900 (2010)

Publication Alert

Geminin and Brahma act antagonistically to regulate EGFR–Ras–MAPK signaling in Drosophila

Anabel Herr, Lisa Mckenzie, Randy Suryadinata, Martin Sadowski, Linda M. Parsons, Boris Sarcevic and Helena E. Richardson

Developmental Biology Volume 344, Issue 1, 1 August 2010, Pages 36-51

Publication Alert

Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase

Sivaraja Vaithiyalingam, Eric M. Warren, Brandt F. Eichman, and Walter J. Chazin

PNAS August 3, 2010 vol. 107 no. 31 13684-13689

Publication Alert

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

Jun-Hyuk Choia, Laura A. Lindsey-Boltza, Michael Kempa, Aaron C. Masonb, Marc S. Woldb, and Aziz Sancara

PNAS August 3, 2010 vol. 107 no. 31 13660-13665

Publication Alert

Identification of a Coiled Coil in Werner Syndrome Protein That Facilitates Multimerization and Promotes Exonuclease Processivity

J. Jefferson P. Perry, Aroumougame Asaithamby, Adam Barnebey, Foad Kiamanesch, David J. Chen, Seungil Han, John A. Tainer, and Steven M. Yannone

J. Biol. Chem. 2010 285: 25699-25707.

Publication Alert

The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication

Rebecca L. Ferguson, Gaetan Pascreau and James L. Maller

Journal of Cell Science 123, 2743-2749 (2010)

Publication Alert

Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA

Oren Parnas, Adi Zipin-Roitman, Boris Pfander, Batia Liefshitz, Yuval Mazor, Shay Ben-Aroya, Stefan Jentsch and Martin Kupiec

The EMBO Journal (2010), 29, 2611 - 2622;

Publication Alert

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA

Máté Gyimesi1, Kata Sarlós1 and Mihály Kovács

Nucleic Acids Research, 2010, Vol. 38, No. 13 4404-4414


Publication Alert

DNA Damage Signaling Recruits the Rtt107-Slx4 Scaffolds via Dpb11 to Mediate Replication Stress Response p300

Patrice Y. Ohouo, Francisco M. Bastos de Oliveira, Beatriz S. Almeida, Marcus B. Smolka

Molecular Cell, Volume 39, Issue 2, 300-306

no postings this week

Publication Alert

Ubiquitylation of FACT by the Cullin-E3 ligase Rtt101 connects FACT to DNA replication

Junhong Han, Qing Li, Laura McCullough, Charisse Kettelkamp, Tim Formosa and Zhiguo Zhang

Genes & Dev. 2010. 24: 1485-1490

Publication Alert

Functions of Alternative Replication Protein A in Initiation and Elongation

Aaron C. Mason, Rupa Roy, Daniel T. Simmons and Marc S. Wold

Biochemistry, 2010, 49 (28), pp 5919–5928

Publication Alert

DNA Replication Is Intrinsically Hindered in Terminally Differentiated Myotubes

Deborah Pajalunga, Eleonora M. R. Puggioni, Alessia Mazzola, Valentina Leva, Alessandra Montecucco, Marco Crescenzi

PLoS ONE 5(7): e11559

no postings this week

Publication Alert

Characterization of physical and functional interactions between eukaryote-like Orc1/Cdc6 proteins and Y-family DNA polymerase in the hyperthermophilic archaeon Sulfolobus solfataricus

Shifan Yang, Hongchao Gong, Lu Zhang, Yi Liu, Zheng-Guo He

Biochemical and Biophysical Research Communications Volume 396, Issue 3, 4 June 2010, Pages 755-762

Publication Alert

The eukaryotic replicative DNA polymerases take shape

Erik Johansson and Stuart A. MacNeill

Trends in Biochemical Sciences Volume 35, Issue 6, June 2010, Pages 339-347

Publication Alert

DNA Replication: Metazoan Sld3 Steps Forward

Yu V. Fu and Johannes C. Walter

Current Biology, Volume 20, Issue 12, R515-R517, 22 June 2010

Publication Alert

Homology explains the functional similarities of Treslin/Ticrr and Sld3

Luis Sanchez-Pulido, John F.X. Diffley and Chris P. Ponting

Current Biology, Volume 20, Issue 12, R509-R510, 22 June 2010

Publication Alert

DNA damage response and tumorigenesis in Mcm2-deficient mice

D Kunnev, M E Rusiniak, A Kudla1, A Freeland, G K Cady1 and S C Pruitt

Oncogene (2010) 29, 3630–3638

Publication Alert

The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin

Philipp Müller, Sookhee Park, Erika Shor, Dana J. Huebert, Christopher L. Warren, Aseem Z. Ansari, Michael Weinreich, Matthew L. Eaton, David M. MacAlpine and Catherine A. Fox

Genes & Dev. 2010. 24: 1418-1433

no postings this week

Publication Alert

G2 phase chromatin lacks determinants of replication timing

Junjie Lu, Feng Li, Christopher S. Murphy, Michael W. Davidson, and David M. Gilbert

JCB vol. 189no. 6967-980

Publication Alert

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

Karim Labib

Genes & Dev. 2010. 24: 1208-1219

Publication Alert

SnapShot: The Replisome

Nina Y. Yao, Mike O'Donnell

Molecular cell 11 June, 2010
 Volume 141, Issue 6 p1088

Publication Alert

Timing, Coordination, and Rhythm: Acrobatics at the DNA Replication Fork

Samir M. Hamdan and Antoine M. van Oijen

J. Biol. Chem. 2010 285: 18979-18983. Open Access

Upcoming meeting

6th UK-Japan Cell Cycle Workshop
10th-14th April, 2011
Lake Windermere (English Lake District)

http://www.gurdon.cam.ac.uk/windermere2011.html

Publication Alert

The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress

Darryl R. Jones, Ajai A. Prasad, Philip K. Chan and Bernard P. Duncker

Cell cycle Volume 9, Issue 10 May 15, 2010 Pages 2018 – 2026

Publication Alert

Interplay between DNA replication and gene expression: a harmonious coexistence

Chrystelle Marica and Marie-Noëlle Prioleau

Current Opinion in Cell Biology Volume 22, Issue 3, June 2010, Pages 277-283

Publication Alert

Replication protein A 32 interacts through a similar binding interface with TIPIN, XPA, and UNG2

Seikh Imtiaz Alia, Jae-Sun Shina, Sung-Hun Baea, Byoungkook Kima and Byong-Seok Cho

The International Journal of Biochemistry & Cell Biology Volume 42, Issue 7, July 2010, Pages 1210-1215

Publication Alert

Fission Yeast Hsk1 (Cdc7) Kinase Is Required After Replication Initiation for Induced Mutagenesis and Proper Response to DNA Alkylation Damage

William P. Dolan, Anh-Huy Le, Henning Schmidt, Ji-Ping Yuan, Marc Green and Susan L. Forsburg

Genetics, Vol. 185, 39-53, May 2010,

Publication Alert

Evolution of DNA Replication Protein Complexes in Eukaryotes and Archaea

Nicholas Chia, Isaac Cann, Gary J. Olsen

PLoS ONE 5(6): e10866.

Publication Alert

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly

John R. Lydeard, Zachary Lipkin-Moore, Yi-Jun Sheu, Bruce Stillman, Peter M. Burgers and James E. Haber

Genes & Dev. 2010. 24: 1133-1144

no postings this week

Publication Alert

Structure of a DNA Polymerase {alpha}-Primase Domain That Docks on the SV40 Helicase and Activates the Viral Primosome

Hao Huang, Brian E. Weiner, Haijiang Zhang, Brian E. Fuller, Yue Gao, Brian M. Wile, Kun Zhao, Diana R. Arnett, Walter J. Chazin, and Ellen Fanning

J. Biol. Chem. 2010 285: 17112-17122.

Publication Alert

Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

Michael G. Kemp, Zafer Akan, Secil Yilmaz, Mary Grillo, Stephanie L. Smith-Roe, Tae-Hong Kang, Marila Cordeiro-Stone, William K. Kaufmann, Robert T. Abraham, Aziz Sancar, and Keziban Unsal-Kacmaz

J. Biol. Chem. 2010 285: 16562-16571.

Publication Alert

Replication through an abasic DNA lesion: structural basis for adenine selectivity

Samra Obeid, Nina Blatter, Ramon Kranaster, Andreas Schnur, Kay Diederichs, Wolfram Welte and Andreas Marx

The EMBO Journal (2010), 29,1738 – 1747

Publication Alert

Human RECQL5{beta} stimulates flap endonuclease 1

Elzbieta Speina, Lale Dawut, Mohammad Hedayati, ZhengMing Wang, Alfred May, Sybille Schwendener, Pavel Janscak, Deborah L. Croteau, and Vilhelm A. Bohr

Nucl. Acids Res. 2010 38: 2904-2916

Publication Alert

The replisome: A nanomachine or a dynamic dance of protein partners?

Gulfem D. Guler and Ellen Fanning

Cancer Cell Volume 9, Issue 9 Pages 1678 – 1683

Publication Alert

Cdc6/Orc1 from Pyrococcus furiosus may act as the origin recognition protein and Mcm helicase recruiter

Masaki Akita, Akinori Adachi, Kie Takemura, Takeshi Yamagami, Fujihiko Matsunaga, Yoshizumi Ishin

Genes to Cells Volume 15 Issue 5, Pages 537 – 552

Publication Alert

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

Alessia Balestrini, Claudia Cosentino, Alessia Errico, Elizabeth Garner & Vincenzo Costanzo

Nature Cell Biology 12, 484 - 491 (2010) 


Publication Alert

Centrosomal Localization of Cyclin E-Cdk2 Is Required for Initiation of DNA Synthesis

Rebecca L. Ferguson,James L. Maller

Current Biology, Volume 20, Issue 9, 856-860, 16 April 2010

Publication Alert

Ctf4p facilitates Mcm10p to promote DNA replication in budding yeast

Jiafeng Wang, Rentian Wu, Yongjun Lu and Chun Liang

Biochemical and Biophysical Research Communications Volume 395, Issue 3, 7 May 2010, Pages 336-341

Publication Alert

Structure and Mutagenesis Studies of the C-terminal Region of Licensing Factor Cdt1 Enable the Identification of Key Residues for Binding to Replicative Helicase Mcm Proteins

JunGoo Jee, Takeshi Mizuno, Katsuhiko Kamada, Hidehito Tochio, Yasumasa Chiba, Ken-ichiro Yanagi, Gentaro Yasuda, Hidekazu Hiroaki, Fumio Hanaoka and Masahiro Shirakawa

The Journal of Biological Chemistry, 285, 15931-15940.

Publication Alert

CRL4Cdt2 E3 Ubiquitin Ligase Monoubiquitinates PCNA to Promote Translesion DNA Synthesis

Kenta Terai, Tarek Abbas, Amir A. Jazaeri, and Anindya Dutta

Molecular Cell, Volume 37, Issue 1, 143-149

no postings this week

Publication Alert

The p12 Subunit of Human Polymerase δ Modulates the Rate and Fidelity of DNA Synthesis

Xiao Meng, Yajing Zhou, Ernest Y. C. Lee, Marietta Y. W. T. Lee and David N. Frick

Biochemistry, 2010, 49 (17), pp 3545–3554

Publication Alert

What Influences DNA Replication Rate in Budding Yeast?

Thomas W. Spiesser, Christian Diener, Matteo Barberis, Edda Klipp

PLoS ONE 5(4): e10203.

Publication Alert

Continued primer synthesis at stalled replication forks contributes to checkpoint activation

Christopher Van, Shan Yan, W. Matthew Michael, Shou Waga, and Karlene A. Cimprich

JCB vol. 189no. 2233-246

Publication Alert

Replication Fork Arrest and rDNA Silencing Are Two Independent and Separable Functions of the Replication Terminator Protein Fob1 of Saccharomyces cerevisiae

Narendra K. Bairwa, Shamsu Zzaman, Bidyut K. Mohanty, and Deepak Bastia

J. Biol. Chem. 2010 285: 12612-12619

Publication Alert

Drf1-dependent Kinase Interacts with Claspin through a Conserved Protein Motif

Daniel A. Gold and William G. Dunphy

J. Biol. Chem. 2010 285: 12638-12646

Publication Alert

Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6

Zhun Wei, Changdong Liu, Xing Wu, Naining Xu, Bo Zhou, Chun Liang, and Guang Zhu

J. Biol. Chem. 2010 285: 12469-12473

Publication Alert

Conserved nucleosome positioning defines replication origins

Matthew L. Eaton, Kyriaki Galani, Sukhyun Kang, Stephen P. Bell and David M. MacAlpine

Genes & Dev. 2010. 24: 748-753

Publication Alert

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

Bret D Freudenthal, Lokesh Gakhar, S Ramaswamy & M Todd Washington

Nature Structural & Molecular Biology 17, 479–484 (2010)

Publication Alert

Dynamic changes in histone acetylation regulate origins of DNA replication


Ashwin Unnikrishnan, Philip R Gafken & Toshio Tsukiyama

Nature Structural & Molecular Biology 17, 430–437 (2010)

Publication Alert

DNA Polymerase: Structure and Function

Edited by A. Berdis

Volume 1804, Issue 5, Pages 1029-1230 (May 2010)

Publication Alert

Replication origins are already licensed in G1 arrested unfertilized sea urchin eggs

Antoine Azea, Claire Fayeta, Laure Lapassetc and A.M. Genevière

Developmental Biology Volume 340, Issue 2, 15 April 2010, Pages 557-570

Publication Alert

Recruitment of Orc6l, a dormant maternal mRNA in mouse oocytes, is essential for DNA replication in 1-cell embryos

Shin Muraia, Paula Steina, Mariano G. Buffonea, Shigeru Yamashita and Richard M. Schultz

Developmental Biology Volume 341, Issue 1, 1 May 2010, Pages 205-212

Publication Alert

Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns

Alessia Errico1 & Vincenzo Costanzo2

EMBO reports (2010) 11, 270 – 278

Publication Alert

Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformation

Domenic Di Paola, Emmanouil Rampakakis, Man Kid Chan, Dina N. Arvanitis, and Maria Zannis-Hadjopoulos

Nucl. Acids Res. 2010 38: 2314-2331; doi:10.1093/nar/gkp1192.

Publication Alert

Early initiation of a replication origin tethered at the nuclear periphery

Hani Ebrahimi E. ,Douglas Robertson, Angela Taddei, Susan M. Gasser, Anne D. Donaldson and Shin-ichiro Hiraga

Journal of Cell Science 123, 1015-1019 (2010)

Publication Alert

Ciz1 cooperates with cyclin-A–CDK2 to activate mammalian DNA replication in vitro

Nikki A. Copeland, Heather E. Sercombe, Justin F. X. Ainscough, and Dawn Coverley

J Cell Sci 2010 123: 1108-1115

Publication Alert

A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability

Zhijiang Yan,Mathieu Delannoy,Chen Ling,Danielle Daee,Fekret Osman,Parameswary A. Muniandy,Xi Shen,Anneke B. Oostra,Hansen Du,Jurgen Steltenpool,Ti Lin,Beatrice Schuster,Chantal Décaillet,Andrzej Stasiak,Alicja Z. Stasiak,Stacie Stone,Maureen E. Hoatlin,Detlev Schindler,Christopher L. Woodcock,Hans Joenje,Ranjan Sen,Johan P. de Winter,Lei Li,Michael M. Seidman,Matthew C. Whitby,Kyungjae Myung,Angelos Constantinou,Weidong Wang


Molecular Cell, Volume 37, Issue 6, 865-878, 26 March 2010

Publication Alert

MHF1-MHF2, a Histone-Fold-Containing Protein Complex, Participates in the Fanconi Anemia Pathway via FANCM

Thiyam Ramsing Singh,Dorina Saro,Abdullah Mahmood Ali,Xiao-Feng Zheng,Chang-hu Du,Michael W. Killen,Aristidis Sachpatzidis ,Kebola Wahengbam ,Andrew J. Pierce ,Yong Xiong ,Patrck Sung , Amom Ruhikanta Meete

Molecular Cell, Volume 37, Issue 6, 879-886, 26 March 2010

Publication Alert

Characterization of a Functional DnaG-Type Primase in Archaea: Implications for a Dual-Primase System

Zhongfeng Zuoa, Cory J. Rodgersa, Andrey L. Mikheikina and Michael A. Trakselis

Journal of Molecular Biology Volume 397, Issue 3, 2 April 2010, Pages 664-676

Publication Alert

Rad17 Plays a Central Role in Establishment of the Interaction between TopBP1 and the Rad9-Hus1-Rad1 Complex at Stalled Replication Forks

Joon Lee, and William G. Dunphy

MBC Vol. 21, Issue 6, 926-935, March 15, 2010

Publication Alert

The SV40 Large T-Antigen Origin Binding Domain Directly Participates in DNA Unwinding

Erin C. Foster and Daniel T. Simmon

Biochemistry, 2010, 49 (10), pp 2087–2096

Publication Alert

CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol ɛ, and GINS in budding yeast

Sachiko Muramatsu1, Kazuyuki Hirai, Yon-Soo Tak, Yoichiro Kamimura and Hiroyuki Araki

Genes & Dev. 2010. 24: 602-612

Publication Alert

Dynamics of Pre-replicative Complex Assembly

Vasiliki Tsakraklides and Stephen P. Bell

The Journal of Biological Chemistry, 285, 9437-9443.

Publication Alert

Influence of the Human Cohesion Establishment Factor Ctf4/AND-1 on DNA Replication

Vladimir P. Bermudez, Andrea Farina, Inger Tappin and Jerard Hurwitz

The Journal of Biological Chemistry, 285, 9493-9505.

Publication Alert

Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs

Kazunori Tachibana, Masashi Mori, Takashi Matsuhira, Tomotake Karino, Takuro Inagaki, Ai Nagayama, Atsuya Nishiyama, Masatoshi Hara, and Takeo Kishimoto3

PNAS March 16, 2010 vol. 107 no. 11 5006-5011

Publication Alert

Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation

Saravanabhavan Thangavel, Ramiro Mendoza-Maldonado, Erika Tissino, Julia M. Sidorova, Jinhu Yin, Weidong Wang, Raymond J. Monnat Jr., Arturo Falaschi, and Alessandro Vindigni

Molecular and Cellular Biology, March 2010, p. 1382-1396, Vol. 30, No. 6

Publication Alert

The DNA Unwinding Element Binding Protein DUE-B Interacts with Cdc45 in Preinitiation Complex Formation

A.Chowdhury, G. Liu, M. Kemp, X. Chen, N. Katrangi, S. Myers, M. Ghosh, J. Yao, Y. Gao, P. Bubulya, and M. Leffak

Molecular and Cellular Biology, March 2010, p. 1495-1507, Vol. 30, No. 6

Publication Alert

Structural diversity and dynamics of genomic replication origins in Schizosaccharomyces pombe

Cristina Cotobal1, Mónica Segurado1 and Francisco Antequera

The EMBO Journal (2010) 29, 934 – 942

Publication Alert

Ultraviolet Radiation Stress Triggers the Down-regulation of Essential Replication Factor Mcm10

Aparna Sharma, Manpreet Kaur, Ananya Kar, Sourabh M. Ranade, and Sandeep Saxena

J. Biol. Chem. 2010 285: 8352-8362.

Publication Alert

Chromosome research
Special issue on Eukaryotic DNA Replication

Volume 18, Number 1 / January, 2010

Publication Alert

Proliferating cell nuclear antigen (Pcna) as a direct downstream target gene of Hoxc8

Hyehyun Mina, Ji-Yeon Leea, Jinwoong Boka, Hyun Joo Chunga and Myoung Hee Kim

Biochemical and Biophysical Research Communications Volume 392, Issue 4, 19 February 2010, Pages 543-547

Publication Alert

Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae

Stephen P. Baker, Jennifer Phillips, Scott Anderson, Qifeng Qiu, Jeffrey Shabanowitz, M. Mitchell Smith, John R. Yates, 3rd, Donald F. Hunt & Patrick A. Grant

Nature Cell Biology 12, 294 - 298 (2010)

Publication Alert

A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination

Dong-Hyun Lee, Yunfeng Pan, Shlomo Kanner, Patrick Sung, James A Borowiec & Dipanjan Chowdhury

Nature Structural & Molecular Biology 17, 365–372 (2010)

Publication Alert

Study of DNA replication in Drosophila using cell free in vitro system

Anton Svitin and Igor Chesnokov

Cell Cycle Volume 9, Issue 4 February 15, 2010 Pages 815 – 819

Publication Alert

FANCM: fork pause, rewind and play

Spencer J Collis and Simon J Boulton

The EMBO Journal (2010), 29,703 – 705

Publication Alert

FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling

Sarah Luke-Glaser, Brian Luke, Simona Grossi and Angelos Constantinou

The EMBO Journal (2010), 29,795 – 805

Publication Alert

ATR activation and replication fork restart are defective in FANCM-deficient cells

Rebekka A Schwab, Andrew N Blackford and Wojciech Niedzwiedz

The EMBO Journal (2010), 29,806 – 818

Publication Alert

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair p492

Eva Petermann, Manuel Luís Orta, Natalia Issaeva, Niklas Schultz, Thomas Helleday

Molecular Cell, Volume 37, Issue 4, 492-502, 26 February 2010

Publication Alert

DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D

Sandeep N. Shah, Patricia L. Opresko, Xiao Meng, Marietta Y. W. T. Lee,and Kristin A. Eckert

Nucl. Acids Res. 2010 38: 1149-1162

Publication Alert

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

Adam R. Leman, Chiaki Noguchi, Candice Y. Lee and Eishi Noguchi

Journal of Cell Science 123, 660-670 (2010)

Publication Alert

Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components

Hua Peng, Mauricio L. Nogueira, Jodi L. Vogel, and Thomas M. Kristie

PNAS February 9, 2010 vol. 107 no. 6 2461-2466

Publication Alert

DNA Replication-Coupled PCNA Mono-Ubiquitination and Polymerase Switching in a Human In Vitro System

Yuji Masuda, Jinlian Piao and Kenji Kamiya

Journal of Molecular Biology Volume 396, Issue 3, 26 February 2010, Pages 487-500

Publication Alert

Acetylation of Dna2 Endonuclease/Helicase and Flap Endonuclease 1 by p300 Promotes DNA Stability by Creating Long Flap Intermediates

Lata Balakrishnan, Jason Stewart, Piotr Polaczek, Judith L. Campbell and Robert A. Bambara

The Journal of Biological Chemistry, 285, 4398-4404.

Publication Alert

Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection

Neerja Karnani, Christopher M. Taylor, Ankit Malhotra, and Anindya Dutta

Mol. Biol. Cell 2010 21: 393-404.

Publication Alert

Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication

Akiko Kumagai, Anna Shevchenko, Andrej Shevchenko, William G. Dunphy

Cell, Volume 140, Issue 3, 349-359, 28 January 2010

Publication Alert

A naturally occurring human RPA subunit homolog does not support DNA replication or cell-cycle progression

Stuart J. Haring, Troy D. Humphreys, and Marc S. Wold

Nucl. Acids Res. 2010 38: 846-858;

Publication Alert

Dna2 is a structure-specific nuclease, with affinity for 5'-flap intermediates

Jason A. Stewart, Judith L. Campbell, and Robert A. Bambara

Nucl. Acids Res. 2010 38: 920-930;

Publication Alert

An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair

Michael G. Kemp, Aaron C. Mason, Aura Carreira, Joyce T. Reardon, Stuart J. Haring, Gloria E. O. Borgstahl, Stephen C. Kowalczykowski, Aziz Sancar, and Marc S. Wold

J. Biol. Chem. 2010 285: 4788-4797.

Publication Alert

Visualisation of PCNA Monoubiquitination In Vivo by Single Pass Spectral Imaging FRET Microscopy

Batters C, Zhu H, Sale JE (2010) .

PLoS ONE 5(2): e9008

Publication Alert

Regulatory mechanism of the initiation step of DNA replication by CDK in budding yeast

Hiroyuki Araki

Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics Volume 1804, Issue 3, March 2010, Pages 520-523

Publication Alert

The dynamic replicon: adapting to a changing cellular environment

John Herrick

BioEssays Volume 32 Issue 2, Pages 153 - 164

Publication Alert

Eukaryotic DNA replication control: Lock and load, then fire

Dirk Remusa and John FX Diffley

Current Opinion in Cell Biology Volume 21, Issue 6, December 2009, Pages 771-777

Publication Alert

The replication fork's five degrees of freedom, their failure and genome rearrangements

T Weinerta, , S Kaochara, H Jonesa, A Paeka and AJ Clarka

Current Opinion in Cell Biology Volume 21, Issue 6, December 2009, Pages 778-784

Publication Alert

Structure and function of the GINS complex, a key component of the eukaryotic replisome

Stuart A. MacNeill

Biochem. J. (2010) 425 (489–500)

Publication Alert

Origin-dependent initiation of DNA replication within telomeric sequences

Isabel Kurth and Jean Gautier

Nucleic Acids Research, 2010, Vol. 38, No. 2 467-476

Publication Alert

Measurement of replication structures at the nanometer scale using super-resolution light microscopy

D. Baddeley, V. O. Chagin, L. Schermelleh, S. Martin, A. Pombo, P. M. Carlton, A. Gahl, P. Domaing, U. Birk1, H. Leonhardt, C. Cremer and M. C. Cardoso

Nucleic Acids Research, 2010, Vol. 38, No. 2 e8

Publication Alert

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

Ivar Ilves, Tatjana Petojevic, James J. Pesavento, Michael R. Botchan

Molecular Cell, Volume 37, Issue 2, 247-258, 29 January 2010

Publication Alert

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels

Alexander M. Thomson, Peter J. Gillespie, and J. Julian Blow

The Journal of Cell Biology, Vol. 188, No. 2, 209-221

Publication Alert

Mechanisms by Which Human DNA Primase Chooses To Polymerize a Nucleoside Triphosphate

Milan Urban, Nicolas Joubert, Byron W. Purse, Michal Hocek and Robert D. Kuchta

Biochemistry, 2010, 49 (4), pp 727–735

Publication Alert

GCN5 Is a Positive Regulator of Origins of DNA Replication in Saccharomyces cerevisiae

Maria Claudia Espinosa, Muhammad Attiq Rehman, Patricia Chisamore-Robert, Daniel Jeffery, Krassimir Yankulov

PLoS ONE 5(1): e8964

Publication Alert

Creating a Novel Origin of Replication through Modulating DNA-Protein Interfaces

F. Curtis Hewitt, R. Jude Samulski

PLoS ONE 5(1): e8850

Publication Alert

HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin

Benoit Miotto and Kevin Struhl

Molecular Cell, Volume 37, Issue 1, 57-66,

Publication Alert

Expanded Roles of the Origin Recognition Complex in the Architecture and Function of Silenced Chromatin in Saccharomyces cerevisiae

Bilge Özaydn and Jasper Rine

Molecular and Cellular Biology, February 2010, p. 626-639, Vol. 30, No. 3

Publication Alert

Leaping forks at inverted repeats

Dana Branzei and Marco Foiani

Genes & Dev. 2010. 24: 5-9

Publication Alert

Activation of Cdc6 by MyoD is associated with the expansion of quiescent myogenic satellite cells

Keman Zhang, Jingfeng Sha, and Marian L. Harter

The Journal of Cell Biology, Vol. 188, No. 1, 39-48

Publication Alert

CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells

Kazumasa Yoshida, Nozomi Sugimoto, Satoko Iwahori, Takashi Yugawa, Mako Narisawa-Saito, Tohru Kiyono and Masatoshi Fujita

Journal of Cell Science 123, 225-235 (2010)

Publication Alert

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

R. Scott Hansen, Sean Thomas, Richard Sandstrom, Theresa K. Canfield, Robert E. Thurman, Molly Weaver, Michael O. Dorschner, Stanley M. Gartler, and John A. Stamatoyannopoulos

PNAS January 5, 2010 vol. 107 no. 1 139-144

Publication Alert

A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability

Danielle L. Daee, Tony M. Mertz and Polina V. Shcherbakova

PNAS January 5, 2010 vol. 107 no. 1 157-162

Publication Alert

The Dbf4–Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

Yi-Jun Sheu1 & Bruce Stillman

Nature 463, 113-117

Publication Alert

Budding Yeast Dbf4 Sequences Required for Cdc7 Kinase Activation and Identification of a Functional Relationship Between the Dbf4 and Rev1 BRCT Domains

Victoria Harkins, Carrie Gabrielse, Louise Haste and Michael Weinreich

Genetics, Vol. 183, 1269-1282, December 2009

Publication Alert

Roles of POLD4, smallest subunit of DNA polymerase δ, in nuclear structures and genomic stability of human cells

Qin Miao Huanga, Tomohiro Akashib, Yuji Masudac, Kenji Kamiyac, Takashi Takahashia and Motoshi Suzuk

Biochemical and Biophysical Research Communications Volume 391, Issue 1, 1 January 2010, Pages 542-546

Publication Alert

High density of weak replication origins in a 75-kb region of chromosome 2 of fission yeast

Dharani D Dubey, Vinay K Srivastava , Aditya S Pratihar and Mukesh P Yadava

Genes to Cells Volume 15 Issue 1, Pages 1 – 12