28 March 2017
publication alert
Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers
Bin Zhu, Longfei Wang, Hitoshi Mitsunobu, Xueling Lu, Alfredo J. Hernandez, Yukari Yoshida-Takashima, Takuro Nunoura, Stanley Tabor, and Charles C. Richardson
PNAS vol. 114 no. 12 E2310–E2318
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Conserved forkhead dimerization motif controls DNA replication timing and spatial organization of chromosomes in S. cerevisiae
A. Zachary Ostrow, Reza Kalhor, Yan Gan, Sandra K. Villwock, Christian Linke, Matteo Barberis, Lin Chen, and Oscar M. Aparicio
PNAS 114 no. 12 E2411–E2419,
publication alert
Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells
Bochao Liu, Jiazhi Hu, Jingna Wang and Daochun Kong
The Journal of Biological Chemistry 292, 4777-4788.
20 March 2017
publication alert
Checkpoint-Independent Regulation of Origin Firing by Mrc1 through Interaction with Hsk1 Kinase
Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Motoshi Hayano, Kyosuke Ueda, Rino Fukatsu, Naoko Kakusho and Hisao Masai
Mol. Cell. Biol. April 2017 vol. 37 no. 7 e00355-16
publication alert
CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination
James M. Dewar, Emily Low, Matthias Mann, Markus Räschle and Johannes C. Walter
Genes & Dev. 2017. 31: 275-290
publication alert
The Human RecQ4 Helicase Contains a Functional RecQ C-terminal Region (RQC) That Is Essential for Activity
Aditya Mojumdar, Matteo De March, Francesca Marino, and Silvia Onesti
J. Biol. Chem. 2017; 292:4176-4184
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Ribosomal Protein S3 Negatively Regulates Unwinding Activity of RecQ-like Helicase 4 through Their Physical Interaction
Ajay Vitthal Patil and Tao-Shih Hsieh
J. Biol. Chem. 2017; 292:4313-4325 F
publication alert
Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation
Shin‐ichiro Hiraga, Tony Ly, Javier Garzón, Zuzana Hořejší, Yoshi‐nobu Ohkubo, Akinori Endo, Chikashi Obuse, Simon J Boulton, Angus I Lamond, Anne D Donaldson
EMBO Reports (2017) 18: 403–419
publication alert
Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization
Yating Wang Abid Khan Anna B. Marks Owen K. Smith Sumanprava Giri Yo-Chuen Lin Rachel Creager David M. MacAlpine Kannanganattu V. Prasanth Mirit I. Aladjem Supriya G. Prasanth
Nucleic Acids Res (2017) 45 (5): 2490-2502.
publication alert
Revealing the role of the product metal in DNA polymerase β catalysis
Lalith Perera Bret D. Freudenthal William A. Beard Lee G. Pedersen Samuel H. Wilson
Nucleic Acids Res (2017) 45 (5): 2736-2745.
publication alert
DNA Replication: How Does a Sliding Clamp Slide?
Nina Y. Yao, Mike O’Donnell
Current biol Volume 27, Issue 5, pR174–R176, 6 March 2017
publication alert
Unearthing worm replication origins
Takayo Sasaki & David M Gilbert
Nature Structural & Molecular Biology 24, 195–196 (2017)
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The gastrula transition reorganizes replication-origin selection in Caenorhabditis elegans
Marta Rodríguez-Martínez, Natalia Pinzón, Charles Ghommidh, Emmanuelle Beyne, Hervé Seitz, Christelle Cayrou & Marcel Méchali
Nature Structural & Molecular Biology 24 290–299 (2017)
publication alert
Open-ringed structure of the Cdt1–Mcm2–7 complex as a precursor of the MCM double hexamer
Yuanliang Zhai, Erchao Cheng, Hao Wu, Ningning Li, Philip Yuk Kwong Yung, Ning Gao & Bik-Kwoon Tye
Nature Structural & Molecular Biology 24 300-308
publication alert
Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing
Simina Ticau, Larry J Friedman, Kanokwan Champasa, Ivan R Corrêa Jr, Jeff Gelles & Stephen P Bell
Nature Structural & Molecular Biology 24 309–315 (2017)
publication alert
Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1
Zuanning Yuan, Alberto Riera, Lin Bai, Jingchuan Sun, Saikat Nandi, Christos Spanos, Zhuo Angel Chen, Marta Barbon, Juri Rappsilber, Bruce Stillman, Christian Speck & Huilin Li
Nature Structural & Molecular Biology 24 316–324 (2017)
5 March 2017
publication alert
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
Hai Dang Nguyen, Tribhuwan Yadav, Sumanprava Giri, Borja Saez, Timothy A. Graubert, Lee Zou
Molecular cell Volume 65, Issue 5, p832–847.e4, 2 March 2017
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