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Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans Vincent Gaggioli , Manuela R. Kieninger , Anna Klucnika, Richard Butler, Philip Zegerman PLoS Genet 16(12): e1008948.

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The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization Yuanliang Yan, Zhijie Xu, Jinzhou Huang, Guijie Guo, Ming Gao, Wootae Kim, Xiangyu Zeng, Jake A Kloeber, Qian Zhu, Fei Zhao ... Show more Nucleic Acids Research, Volume 48, Issue 22, 16 December 2020, Pages 12711–12726,

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Developmental differences in genome replication program and origin activation Cathia Rausch, Patrick Weber, Paulina Prorok, David Hörl, Andreas Maiser, Anne Lehmkuhl, Vadim O Chagin, Corella S Casas-Delucchi, Heinrich Leonhardt, M Cristina Cardoso Author Notes Nucleic Acids Research, Volume 48, Issue 22, 16 December 2020, Pages 12751–12777,

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The E3 ligase RFWD3 stabilizes ORC in a p53-dependent manner Rosaline Y.C. Hsu , Sumanprava Giri , Yating Wang , Yo-Chuen Lin , Dazhen Liu , Susan Wopat , Arindam Chakraborty , Kannanganattu V. Prasanth & Supriya G. Prasanth Cell cycle Volume 19, 2020 - Issue 21 Pages 2927-2938 |

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Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε Vladislav O. Sviderskiy, Lili Blumenberg, Elizabeth Gorodetsky, Sylvia Adams, Kelly V. Ruggles, Richard Possemato Mol Cell VOLUME 80, ISSUE 4, P682-698.E7,

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Pif1, RPA, and FEN1 modulate the ability of DNA polymerase δ to overcome protein barriers during DNA synthesis Melanie A. Sparks, Peter M. Burgers* and Roberto Galletto The Journal of Biological Chemistry 295, 15883-15891.

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Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy Kouta Mayanagi, Keisuke Oki, Naoyuki Miyazaki, Sonoko Ishino, Takeshi Yamagami, Kosuke Morikawa, Kenji Iwasaki, Daisuke Kohda, Tsuyoshi Shirai & Yoshizumi Ishino BMC Biology volume 18, Article number: 152 (2020)

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Equilibrium between nascent and parental MCM proteins protects replicating genomes Hana Sedlackova, Maj-Britt Rask, Rajat Gupta, Chunaram Choudhary, Kumar Somyajit & Jiri Lukas Nature (2020).

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Polymerization and editing modes of a high-fidelity DNA polymerase are linked by a well-defined path Thomas Dodd, Margherita Botto, Fabian Paul, Rafael Fernandez-Leiro , Meindert H. Lamers and Ivaylo Ivanov NATURE COMMUNICATIONS (2020)11:5379

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The DNA replication fork suppresses CMG unloading from chromatin before termination Emily Low, Gheorghe Chistol, Manal S. Zaher, Olga V. Kochenova, and Johannes C. Walter GENES & DEVELOPMENT 34:1534–1545

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PRIM1 deficiency causes a distinctive primordial dwarfism syndrome David A. Parry,Lukas Tamayo-Orrego, Paula Carroll, Joseph A. Marsh, Philip Greene, Olga Murina, Carolina Uggenti,Andrea Leitch, The Scottish Genomes Partnership, Rita Káposzta, Gabriella Merő, Andrea Nagy, Brigitta Orlik, Balázs Kovács-Pászthy, Alan J. Quigley,Magdolna Riszter, Julia Rankin, Martin A.M. Reijns, Katalin Szakszon, and Andrew P. Jackson GENES & DEVELOPMENT 34:1520–1533

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Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication Ikenna Obi, Matilda Rentoft, Vandana Singh, Jan Jamroskovic, Karam Chand, Erik Chorell, Fredrik Westerlund, Nasim Sabouri Nucleic Acids Research, Volume 48, Issue 19, 4 November 2020, Pages 10998–11015,

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CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication Haihua Feng, Jingchen Lu, Xiaotian Song, Angkana Thongkum, Fan Zhang, Lihong Lou, Ofer Reizes, Alexandru Almasan, Zihua Gong Nucleic Acids Research, Volume 48, Issue 19, 4 November 2020, Pages 10940–10952,

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A hand-off of DNA between archaeal polymerases allows high-fidelity replication to resume at a discrete intermediate three bases past 8-oxoguanine Matthew T Cranford, Joseph D Kaszubowski, Michael A Trakselis Nucleic Acids Research, Volume 48, Issue 19, 4 November 2020, Pages 10986–10997,

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Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA Naining Xu, Yingying You, Changdong Liu, Maxim Balasov, Lee Tung Lun, Yanyan Geng, Chun Po Fung, Haitao Miao, Honglei Tian, To To Choy Xiao Shi, Zhuming Fan, Bo Zhou, Katarina Akhmetova, Rahman Ud Din, Hongyu Yang, Quan Hao, Peiyuan Qian, Igor Chesnokov, Guang Zhu Nucleic Acids Research, Volume 48, Issue 19, 4 November 2020, Pages 11146–11161,

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Prevention of unwanted recombination at damaged replication forks Carl P. Lehmann, Alberto Jiménez-Martín, Dana Branzei & José Antonio Tercero Current Genetics volume 66, pages1045–1051(2020)

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Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue Rowin Appanah, David Jones, Benoît Falquet & Ulrich Rass Current Genetics volume 66, pages1085–1092(2020)

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How yeast cells deal with stalled replication forks Matan Arbel, Batia Liefshitz & Martin Kupiec Current Genetics volume 66, pages911–915(2020)

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Positive and Negative Regulation of DNA Replication Initiation Qiliang Din, Amnon Koren TIGS VOLUME 36, ISSUE 11, P868-879, NOVEMBER 01, 2020

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Molecular mechanisms of eukaryotic origin initiation, replication fork progression, and chromatin maintenance Zuanning Yuan; Huilin Li Biochem J (2020) 477 (18): 3499–3525.

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Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair Jacob V. Layer, Lydie Debaize, Alexandria Van Scoyk, Nealia C. House, Alexander J. Brown, Yunpeng Liu, Kristen E. Stevenson, Michael Hemann, Steven A. Roberts, Brendan D. Price, David M. Weinstock, and Tovah A. Day PNAS November 3, 2020 117 (44) 27566-27577;

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Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain Caroline Brossas, Anne-Laure Valton, Sergey V Venev, Sabarinadh Chilaka, Antonin Counillon, Marc Laurent, Coralie Goncalves, Bénédicte Duriez, Franck Picard, Job Dekker & Marie-Noëlle Prioleau The EMBO Journal (2020) 39: e99520

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Evolution of DNA replication origin specification and gene silencing mechanisms Y. Hu, A. Tareen, Y-J. Sheu, W. T. Ireland, C. Speck, H. Li, L. Joshua-Tor, J. B. Kinney & B. Stillman Nature Communications volume 11, Article number: 5175 (2020)

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Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots Emily E. Wear , Jawon Song, Gregory J. Zynda, Leigh Mickelson-Young, Chantal LeBlanc, Tae-Jin Lee, David O. Deppong, George C. Allen, Robert A. Martienssen, Matthew W. Vaughn, Linda Hanley-Bowdoin, William F. Thompson PLoS Genet 16(10): e1008623.

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γH2AX in the S Phase after UV Irradiation Corresponds to DNA Replication and Does Not Report on the Extent of DNA Damage Shivnarayan Dhuppar, Sitara Roy, Aprotim Mazumder Molecular and Cellular Biology Sep 2020, 40 (20) e00328-20

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Juvenile hormone acts through FoxO to promote Cdc2 and Orc5 transcription for polyploidy-dependent vitellogenesis Zhongxia Wu, Qiongjie He, Baojuan Zeng, Haodan Zhou, Shutang Zhou Development 2020 147:dev188813

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Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go Vanessa Kellner, Duncan J. Smith Molecular Cell VOLUME 80, ISSUE 1, P6-8, OCTOBER 01, 2020

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Processive Activity of Replicative DNA Polymerases in the Replisome of Live Eukaryotic Cells Nitin Kapadia, Ziad W. El-Hajj, Huan Zheng, Thomas R. Beattie, Angela Yu, Rodrigo Reyes-Lamothe Molecular Cell VOLUME 80, ISSUE 1, P114-126.E8,

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A predictable conserved DNA base composition signature defines human core DNA replication origins Ildem Akerman, Bahar Kasaai, Alina Bazarova, Pau Biak Sang, Isabelle Peiffer, Marie Artufel, Romain Derelle, Gabrielle Smith, Marta Rodriguez-Martinez, Manuela Romano, Sandrina Kinet, Peter Tino, Charles Theillet, Naomi Taylor, Benoit Ballester & Marcel Méchali Nature Communications volume 11, Article number: 4826 (2020)

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Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant Chelsea R Bulock, Xuanxuan Xing, Polina V Shcherbakova Nucleic Acids Research, Volume 48, Issue 16, 18 September 2020, Pages 9124–9134

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Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication Leticia K Lerner, Sandro Holzer, Mairi L Kilkenny, Saša Šviković, Pierre Mura, Davide Schiavone, Cara B Eldridge, Alice Bittleston, Joseph D Maman, Dana Branzei, Katherine Stott, Luca Pellegrini, Julian E Sale EMBO J (2020)39:e104185

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A Timeless Tale: G4 structure recognition by the fork protection complex triggers unwinding by DDX11 helicase Catherine H Freudenreich EMBO J (2020)39:e106305

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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability Lisa Prendergast, Urszula L. McClurg, Rossitsa Hristova, Rolando Berlinguer-Palmini, Sarah Greener, Katie Veitch, Inmaculada Hernandez, Philippe Pasero, Daniel Rico, Jonathan M. G. Higgins, Anastas Gospodinov & Manolis Papamichos-Chronakis Nature Communications volume 11, Article number: 4534 (2020)

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DNA polymerase stalling at structured DNA constrains the expansion of short tandem repeats Pierre Murat, Guillaume Guilbaud & Julian E. Sale Genome Biology volume 21, Article number: 209 (2020) https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02124-x

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Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6 Jan Marten Schmidt & Franziska Bleichert Nature Communications volume 11, Article number: 4263 (2020) https://www.nature.com/articles/s41467-020-18067-7?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200826&WT.ec_id=NCOMMS-20200826&sap-outbound-id=0A5724557941A34A18F6B5D7E75E5E98C35DC010

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A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation Estrella Guarino Almeida, Xavier Renaudin, Ashok R Venkitaraman Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 7844–7855, https://academic.oup.com/nar/article/48/14/7844/5870336

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Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication Katy Stokes, Alicja Winczura, Boyuan Song, Giacomo De Piccoli, Daniel B Grabarczyk Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 8128–8145 https://academic.oup.com/nar/article/48/14/8128/5862685

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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites Alexy Promonet, Ismaël Padioleau, Yaqun Liu, Lionel Sanz, Anna Biernacka, Anne-Lyne Schmitz, Magdalena Skrzypczak, Amélie Sarrazin, Clément Mettling, Maga Rowicka, Krzysztof Ginalski, Frédéric Chedin, Chun-Long Chen, Yea-Lih Lin & Philippe Pasero Nature Communications volume 11, Article number: 3940 (2020) https://www.nature.com/articles/s41467-020-17858-2?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200812&WT.ec_id=NCOMMS-20200812&sap-outbound-id=56E910EFFBEC9EB2C12007131304B60C4CA541E5

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Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 Zuanning Yuan, Sarah Schneider, Thomas Dodd, Alberto Riera, Lin Bai, Chunli Yan, Indiana Magdalou,Ivaylo Ivanov, Bruce Stillman, Huilin Li, and Christian Speck PNAS July 28, 2020 117 (30) 17747-17756 https://www.pnas.org/content/117/30/17747.short?rss=1%20https://www.nature.com/articles/s41467-020-17449-1?utm_source=ncomms_etoc&utm_medium=email&utm_campaign=toc_41467_11_1&utm_content=20200812&WT.ec_id=NCOMMS-20200812&sap-outbound-id=56E910EFFBEC9EB2C12007131304B60C4CA541E5

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Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution Andrea Björkman, Søren L. Johansen, Lin Lin, Mike Schertzer, Dimitris C. Kanellis, Anna-Maria Katsori, Søren T. Christensen, Yonglun Luo, Jens S. Andersen, Simon J. Elsässer, Arturo Londono-Vallejo, Jiri Bartek and Kenneth B. Schou Genes & Dev. 2020. 34: 1065-1074 http://genesdev.cshlp.org/content/34/15-16/1065.short?rss=1

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Sir2 takes affirmative action to ensure equal opportunity in replication origin licensing Armelle Lengronne and View ORCID ProfilePhilippe Pasero PNAS July 21, 2020 117 (29) 16723-16725 https://www.pnas.org/content/117/29/16723.short?rss=1

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Active Replication Checkpoint Drives Genome Instability in Fission Yeast mcm4 Mutant Seong Min Kim, Susan L. Forsburg Mol Cell Biol 40:e00033-20. https://mcb.asm.org/content/40/14/e00033-20

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RIF1 controls replication initiation and homologous recombination repair in a radiation dose-dependent manner Yuichiro Saito, Junya Kobayashi, Masato T. Kanemaki, Kenshi Komatsu Journal of Cell Science 2020 133 https://jcs.biologists.org/content/133/12/jcs240036?rss=1

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Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome Zuanning Yuan, Roxana Georgescu, Grant D. Schauer, Michael E. O’Donnell & Huilin Li NATURE COMMUNICATIONS | (2020)11:3156 https://www.nature.com/articles/s41467-020-16910-5.pdf

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status Karl P. Hodel, Meijuan J.S. Sun, Nathan Ungerleider, Hua Lu, James B. McLachlan, Zachary F. Pursell Mol Cell VOLUME 78, ISSUE 6, P1166-1177.E6

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Histone acetyltransferase 1 is required for DNA replication fork function and stability Paula A. Agudelo Garcia1, Callie M. Lovejoy, Prabakaran Nagarajan, Dongju Park, Liudmila V. Popova, Michael A. Freitas and Mark R. Parthun The Journal of Biological Chemistry 295, 8363-8373.

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Mdm4 supports DNA replication in a p53-independent fashion Kai Wohlberedt, Ina Klusmann, Polina K. Derevyanko, Kester Henningsen, Josephine Ann Mun Yee Choo, Valentina Manzini, Anna Magerhans, Celeste Giansanti, Christine M. Eischen, Aart G. Jochemsen & Matthias Dobbelstein Oncogene volume 39, pages4828–4843(2020)

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Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork Domagoj Baretić, Michael Jenkyn-Bedford, Valentina Aria, Giuseppe Cannone, Mark Skehel, Joseph T.P. Yeeles Mol Cell 78, ISSUE 5, P926-940.E13,

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Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq Annie M. Sriramachandran, Giuseppe Petrosino, María Méndez-Lago, Axel J. Schäfer, Liliana S. Batista-Nascimento, Nicola Zilio,Helle D. Ulrich Mol cell VOLUME 78, ISSUE 5, P975-985.E7,

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Cohesin Causes Replicative DNA Damage by Trapping DNA Topological Stress Nicola Elizabeth Minchell, Andrea Keszthelyi, Jonathan Baxter Mol cell VOLUME 78, ISSUE 4, P739-751.E8, MAY 21, 2020

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Division of Labor between PCNA Loaders in DNA Replication and Sister Chromatid Cohesion Establishment Hon Wing Liu, Céline Bouchoux, Mélanie Panarotto, Yasutaka Kakui, Harshil Patel, Frank Uhlmann Mol Cell VOLUME 78, ISSUE 4, P725-738.E4, MAY 21, 2020

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Binding-Induced Conformational Changes Involved in Sliding Clamp PCNA and DNA Polymerase DPO4 Wen-Ting Chu, Zucai Suo, Jin Wang iScience VOLUME 23, ISSUE 5, 101117, MAY 22, 2020

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DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis Xiangzhou Meng, Lei Wei, Sujan Devbhandari, Tuo Zhang, Jenny Xiang, Dirk Remus & Xiaolan Zhao Nature Communications volume 11, Article number: 2437 (2020)

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Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine Sathya Balachander, Alli L. Gombolay, Taehwan Yang, Penghao Xu, Gary Newnam, Havva Keskin, Waleed M. M. El-Sayed, Anton V. Bryksin, Sijia Tao, Nicole E. Bowen, Raymond F. Schinazi, Baek Kim, Kyung Duk Koh, Fredrik O. Vannberg & Francesca Storici Nature Communications volume 11, Article number: 2447 (2020)

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DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival Aarti Yadav, Varshni Sharma , Jyoti Pal , Pallavi Gulati, Manisha Goel, Udita Chandra, Neha Bansal, Swati Saha PLoS Pathog 16(5): e1008190.

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Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA Clément Madru, Ghislaine Henneke, Pierre Raia, Inès Hugonneau-Beaufet, Gérard Pehau-Arnaudet, Patrick England, Erik Lindahl, Marc Delarue, Marta Carroni & Ludovic Sauguet Nature Communications volume 11, Article number: 1591 (2020)

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Replication Fork Barriers and Topological Barriers: Progression of DNA Replication Relies on DNA Topology Ahead of Forks Jorge B. Schvartzman Pablo Hernández Dora B. Krimer Bioessays Volume 42, Issue5 May 2020 1900204

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Determinants of Replication-Fork Pausing at tRNA Genes in Saccharomyces cerevisiae Rani Yeung and Duncan J. Smith GENETICS April 1, 2020 vol. 214 no. 4 825-838

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Rif1 Functions in a Tissue-Specific Manner To Control Replication Timing Through Its PP1-Binding Motif Robin L. Armstrong, Souradip Das, Christina A. Hill, Robert J. Duronio and Jared T. Nordman GENETICS May 1, 2020 vol. 215 no. 1 75-87

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How yeast cells deal with stalled replication forks Matan Arbel, Batia Liefshitz & Martin Kupiec Current Genetics

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Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication Romain Forey,Ana Poveda,Sushma Sharma,Antoine Barthe,Ismael Padioleau,Claire Renard,Robin Lambert,Magdalena Skrzypczak,Krzysztof Ginalski,Armelle Lengronne,Andrei Chabes,Benjamin Pardo,Philippe Pasero Mol Cell VOLUME 78, ISSUE 3, P396-410.E4,

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Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation Sarina Y. Porcella, Natasha C. Koussa, Colin P. Tang, Daphne N. Kramer, Priyanka Srivastava, Duncan J. Smith PLoS Genet 16(5): e1008755

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RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome Wei Wu, Rahul Bhowmick, Ivan Vogel, Özgün Özer, Fiorella Ghisays, Roshan S. Thakur, Esther Sanchez de Leon, Philipp H. Richter, Liqun Ren, John H. Petrini, Ian D. Hickson & Ying Liu Nature Structural & Molecular Biology volume 27, pages424–437(2020)

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SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations A. Takedachi, E. Despras, S. Scaglione, R. Guérois, J. H. Guervilly, M. Blin, S. Audebert, L. Camoin, Z. Hasanova, M. Schertzer, A. Guille, D. Churikov, I. Callebaut, V. Naim, M. Chaffanet, J. P. Borg, F. Bertucci, P. Revy, D. Birnbaum, A. Londoño-Vallejo, P. L. Kannouche & P. H. L. Gaillard Nature Structural & Molecular Biology volume 27, pages438–449(2020)

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Reconstitution of translesion synthesis reveals a mechanism of eukaryotic DNA replication restart Thomas A. Guilliam & Joseph T. P. Yeeles Nature Structural & Molecular Biology volume 27, pages450–460(2020)

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Rad53 limits CMG helicase uncoupling from DNA synthesis at replication forks Sujan Devbhandari & Dirk Remus Nature Structural & Molecular Biology volume 27, pages461–471(2020)

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Budding yeast complete DNA synthesis after chromosome segregation begins Tsvetomira Ivanova, Michael Maier, Alsu Missarova, Céline Ziegler-Birling, Monica Dam, Mercè Gomar-Alba, Lucas B. Carey & Manuel Mendoza Nature Communications volume 11, Article number: 2267 (2020)

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Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer Damon R. Reed Mark G. Alexandrow Bioessays Volume42, Issue4

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Opportunities for new studies of nuclear DNA replication enzymology in budding yeast Marta A. Garbacz, Scott A. Lujan & Thomas A. Kunkel Current Genetics volume 66, pages299–302(2020)

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SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development Lucia Falbo, Erica Raspelli, Francesco Romeo, Simona Fiorani, Federica Pezzimenti, Francesca Casagrande, Ilaria Costa, Dario Parazzoli & Vincenzo Costanzo NATURE COMMUNICATIONS | (2020)11:1345

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FAM111A protects replication forks from protein obstacles via its trypsin-like domain Yusuke Kojima, Yuka Machida, Sowmiya Palani, Thomas R. Caulfield, Evette S. Radisky, Scott H. Kaufmann & Yuichi J. Machida NATURE COMMUNICATIONS | (2020)11:1318

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DNA polymerase δ proofreads errors made by DNA polymerase ε Chelsea R. Bulock, Xuanxuan Xing, and Polina V. Shcherbakova PNAS March 17, 2020 117 (11) 6035-6041

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Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO–POL enzyme Shreya Ghosh, Yehuda Goldgur, Stewart Shuman Nucleic Acids Research, Volume 48, Issue 6, 06 April 2020, Pages 3165–3180,

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Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles Anupam Singh, Manjula Pandey, Divya Nandakumar, Kevin D Raney, Y Whitney Yin, Smita S Patel EMBO J (2020)39:e103367

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Structure of the processive human Pol δ holoenzyme Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu, Fahad Rashid, Nekane Merino, Timothy J. Ragan, Christos G. Savva, Manal S. Zaher, Afnan Shirbini, Francisco J. Blanco, Samir M. Hamdan & Alfredo De Biasio Nature Communications volume 11, Article number: 1109 (2020)

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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells Annabel Quinet, Stephanie Tirman, Jessica Jackson, Saša Šviković, Delphine Lemaçon, Denisse Carvajal-Maldonado, Daniel González-Acosta, Alexandre T. Vessoni, Emily Cybulla, Matthew Wood, Steven Tavis, Luis F.Z. Batista, Juan Méndez, Julian E. Sale, Alessandro Vindigni Mol Cell VOLUME 77, ISSUE 3, P461-474.E9,

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Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer Hu Fang, Jayne A. Barbour, Rebecca C. Poulos, Riku Katainen, Lauri A. Aaltonen, Jason W. H. Wong PLoS Genet 16(2): e1008572

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Inactivating Mutations in Exonuclease and Polymerase Domains in DNA Polymerase Delta Alter Sensitivities to Inhibitors of dNTP Synthesis Jiaming Zhang, Deyin Hou, James Annis, Forough Sargolzaeiaval, Julia Appelbaum, Eishi Takahashi, George M. Martin, Alan Herr, and Junko Oshima DNA and Cell BiologyVol. 39, No. 1

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DNA unwinding mechanism of a eukaryotic replicative CMG helicase Zuanning Yuan, Roxana Georgescu, Lin Bai, Dan Zhang, Huilin Li & Michael E. O’Donnell Nature Communications volume 11, Article number: 688 (2020)

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HBO1 (KAT7) Does Not Have an Essential Role in Cell Proliferation, DNA Replication, or Histone 4 Acetylation in Human Cells Andrew J. Kueh, Samantha Eccles, Leonie Tang, Alexandra L. Garnham, Rose E. May, Marco J. Herold, Gordon K. Smyth, Anne K. Voss, Tim Thomas Mol Cell Biol 40:e00506-19.

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Mechanisms of replication origin licensing: a structural perspective Franziska Bleichert Current Opinion in Structural BiologyVolume 59, December 2019, Pages 195-204

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Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication Jacob S. Lewis, Lisanne M. Spenkelink, Grant D. Schauer, Callum Kay, Michael E. O’Donnell, Antoine M. van Oijen Mol Cell VOLUME 77, ISSUE 1, P17-25.E5, JANUARY 02, 2020

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Processing of DNA Polymerase-Blocking Lesions during Genome Replication Is Spatially and Temporally Segregated from Replication Forks Ronald P. Wong, Néstor García-Rodríguez, Nicola Zilio, Mária Hanulová, Helle D. Ulrich Mol Cell VOLUME 77, ISSUE 1, P3-16.E4, JANUARY 02, 2020

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Fork pausing complex engages topoisomerases at the replisome Maksym Shyian, Benjamin Albert, Andreja Moset Zupan, Vitalii Ivanitsa, Gabriel Charbonnet, Daniel Dilg and David Shore Genes & Dev. 2020. 34: 87-98

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Top1 and Top2 promote replication fork arrest at a programmed pause site Mélanie V. Larcher and Philippe Pasero Genes & Dev. 2020. 34: 1-3

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A gatekeeping function of the replicative polymerase controls pathway choice in the resolution of lesion-stalled replisomes Seungwoo Chang, Karel Naiman, Elizabeth S. Thrall, James E. Kath, Slobodan Jergic, Nicholas E. Dixon, Robert P. Fuchs, and Joseph J. Loparo PNAS December 17, 2019 116 (51) 25591-25601

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Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Malgorzata Alabrudzinska, Adrianna Skoneczna, Piotr Jonczyk, Michal Dmowski , Iwona J. Fijalkowska PLoS Genet 15(12): e1008494.