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Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks Romain Drissi, Anaïs Chauvin, Alyson McKenna, Dominique Lévesque, Simon Blais-Brochu, Dominique Jean & François-Michel Boisvert Cell Cycle, 17:23, 2593-2609

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A structural view of the initiators for chromosome replication Kin Fan On, Matt Jaremko, Bruce Stillman, Leemor Joshua-Tor Current Opinion in Structural Biology Volume 53, December 2018, Pages 131-139

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Eukaryotic DNA polymerases Rinku Jain, Aneel Aggarwal, Olga Rechkoblit Current Opinion in Structural Biology Volume 53, December 2018, Pages 77-87

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CDK phosphorylation regulates Mcm3 degradation in budding yeast KaoriYamamoto, NishihoMakino, MasayoshiNagai, HiroyukiAraki, TakashiUshimaru Biochemical and Biophysical Research Communications Volume 506, Issue 3, 30 November 2018, Pages 680-684 https://www.sciencedirect.com/science/article/pii/S0006291X18323283

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Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures Danielle Dahan Ioannis Tsirkas Daniel Dovrat Melanie A Sparks Saurabh P Singh Roberto Galletto Amir Aharoni Nucleic Acids Research, Volume 46, Issue 22, 14 December 2018, Pages 11847–11857,

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Conformational Flexibility of Ubiquitin-Modified and SUMO-Modified PCNA Shown by Full-Ensemble Hybrid Methods Kyle T.Powers Emily D.Lavering M. ToddWashington Journal of Molecular Biology Volume 430, Issue 24, 7 December 2018, Pages 5294-5303

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Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome OPEN Panchali Goswami, Ferdos Abid Ali, Max E. Douglas, Julia Locke, Andrew Purkiss, Agnieszka Janska, Patrik Eickhoff, Anne Early, Andrea Nans, Alan M. C. Cheung, John F. X. Diffley & Alessandro Costa 29 November 2018 | doi: 10.1038/s41467-018-07417-1

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Proliferating cell nuclear antigen interacts with the CRL4 ubiquitin ligase subunit CDT2 in DNA synthesis–induced degradation of CDT1 Feng Leng, Lovely Saxena, Nam Hoang, Chunxiao Zhang, Logan Lee, Wenjing Li, Xiaoshan Gong, Fei Lu, Hong Sun and Hui Zhang J. Biol. Chem. 2018; 293:18879-18889

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Regulation of the Minichromosome Maintenance Protein 3 (MCM3) Chromatin Binding by the Prolyl Isomerase Pin1 Michael Schumann, Miroslav Malešević, Erik Hinze, Sebastian Mathea, ... Cordelia Schiene-Fischer J Mol Biol Volume 430, Issue 24, 7 December 2018, Pages 5169-5181

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Cdt1 variants reveal unanticipated aspects of interactions with cyclin/CDK and MCM important for normal genome replication Pedro N. Pozo, Jacob P. Matson, Yasemin Cole, Katarzyna M. Kedziora, Gavin D. Grant, Brenda Temple, and Jeanette Gowen Cook Molecular Biology of the Cell 29 Pages:2989–3002

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Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication Xinjian Li, Xu Qian, Hongfei Jiang, Yan Xia, Yanhua Zheng, Jing Li, Bi-Jun Huang, Jing Fang, Chao-Nan Qian, Tao Jiang, Yi-Xin Zeng, Zhimin Lu Molecular Cell VOLUME 72, ISSUE 4, P650-660.E8, NOVEMBER 15, 2018

Snapshots of archaeal DNA replication and repair in living cells using super-resolution imaging Floriane Delpech; Yoann Collien; Pierre Mahou; Emmanuel Beaurepaire; Hannu Myllykallio Roxane Lestini Nucleic Acids Research, Volume 46, Issue 20, 16 November 2018, Pages 10757–10770

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Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms David V. Phizicky and Stephen P. Bell Chromosoma December 2018, Volume 127, Issue 4, pp 515–527

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Rapid high-resolution measurement of DNA replication timing by droplet digital PCR Dzmitry G Batrakou Emma D Heron Conrad A Nieduszynski Nucleic Acids Research, Volume 46, Issue 19, 2 November 2018, Pages e112,

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Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions Xia Wu Hadi Kabalane Malik Kahli Nataliya Petryk Bastien Laperrousaz Yan Jaszczyszyn Guenola Drillon Frank-Emmanuel Nicolini Gaëlle Perot Aude Robert Nucleic Acids Research, Volume 46, Issue 19, 2 November 2018, Pages 10157–10172,

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Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition Nishita Shastri, Yu-Chen Tsai, Suzanne Hile, ..., Liliya A. Yatsunyk, Kristin A. Eckert, Eric J. Brown Molecular Cell 72, 222–238

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DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier Kohji Hizume, Shizuko Endo, Sachiko Muramatsu, Takehiko Kobayashi and Hiroyuki Araki Genes & Dev. 2018. 32: 1315-1320

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Control of Hexamerization, Assembly, and Excluded Strand Specificity for the Sulfolobus solfataricus MCM Helicase Brian W. Graham, Michael E. Bougoulias, Katie L. Dodge, Carly T. Thaxton, Danae Olaso, Yeqing Tao, Nicolas L. Young, Alan G. Marshall, and Michael A. Trakselis Biochemistry October 2, 2018 Volume 57, Issue 395672–5682

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The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands Haiyun Gan, Albert Serra-Cardona, Xu Hua, Hui Zhou, Karim Labib, Chuanhe Yu, Zhiguo Zhang Mol Cell VOLUME 72, ISSUE 1, P140-151.E3, OCTOBER 04, 2018

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POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication Roberto Bellelli, Ondrej Belan, Valerie E. Pye, Camille Clement, Sarah L. Maslen, J. Mark Skehel, Peter Cherepanov, Genevieve Almouzni,Simon J. Boulton 5 Molecular Cell 72, 112–126

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Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism Shivangi Agarwal, Kyle Paul Smith, Yizhuo Zhou, Aussie Suzuki, Richard J. McKenney, Dileep Varma JCB 217 (10): 3446

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MCM2 promotes symmetric inheritance of modified histones during DNA replication Nataliya Petryk, Maria Dalby, Alice Wenger, Caroline B. Stromme, Anne Strandsby, Robin Andersson, Anja Groth Science 28 Sep 2018:Vol. 361, Issue 6409, pp. 1389-1392

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A mechanism for preventing asymmetric histone segregation onto replicating DNA strands Chuanhe Yu1, Haiyun Gan2, Albert Serra-Cardona, Lin Zhang, Songlin Gan, Sushma Sharma, Erik Johansson, Andrei Chabes, Rui-Ming Xu, Zhiguo Zhang Science 28 Sep 2018:Vol. 361, Issue 6409, pp. 1386-1389

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Cellular senescence induces replication stress with almost no affect on DNA replication timing Juan Carlos Rivera-Mulia, Hélène Schwerer, Emilie Besnard, Romain Desprat, Claudia Trevilla-Garcia, Jiao Sima, Paul Bensadoun, Anissa Zouaoui, David M. Gilbert & Jean-Marc Lemaitre Cell Cycle Volume 17, 2018 - Issue 13 Pages 1667-1681

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Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks Shin‐ichiro Hiraga, Chandre Monerawela, Yuki Katou, Sophie Shaw, Kate RM Clark, Katsuhiko Shirahige, Anne D Donaldson MBO reports (2018) 19, e46222

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Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments Hongwei Liao, Fang Ji,Thomas Helleday, Songmin Ying EMBO reports (2018) 19, e46263

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Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase Jonas Andreas Schmid, Matteo Berti, Franziska Walser, Maria Chiara Raso, Fabian Schmid, Jana Krietsch, Henriette Stoy, Katharina Zwicky, Sebastian Ursich, Raimundo Freire, Massimo Lopes, Lorenza Penengo Mol Cell VOLUME 71, ISSUE 6, P897-910.E8, SEPTEMBER 20, 2018

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Germline DNA replication timing shapes mammalian genome composition Yishai Yehuda Britny Blumenfeld Nina Mayorek Kirill Makedonski Oriya Vardi Leonor Cohen-Daniel Yousef Mansour Shulamit Baror-Sebban Hagit Masika Marganit Farago et al Nucleic Acids Research, Volume 46, Issue 16, 19 September 2018, Pages 8299–8310,

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Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells Sumeet Poudel, Jianhong Yao, Michael G. Kemp and Michael Leffak The Journal of Biological Chemistry 293, 14497-14506

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Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism Shivangi Agarwal, Kyle Paul Smith, Yizhuo Zhou, Aussie Suzuki, Richard J. McKenney, Dileep Varma JCB September 3, 2018 Volume 217, No. 9

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Rtt105 functions as a chaperone for replication protein A to preserve genome stability Shuqi Li, Zhiyun Xu, Jiawei Xu,Linyu Zuo, Chuanhe Yu, Pu Zheng, Haiyun Gan, Xuezheng Wang, Longtu Li, Sushma Sharma, Andrei Chabes, Di Li, Sheng Wang, Sihao Zheng, Jinbao Li, Xuefeng Chen, Yujie Sun, Dongyi Xu, Junhong Han, Kuiming Chan, Zhi Qi, Feng, Qing Li The EMBO Journal (2018) 37, e99154

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Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse Anthony Tubbs, Sriram Sridharan, Niek van Wietmarschen, Yaakov Maman, Elsa Callen, Andre Stanlie, Wei Wu, Xia Wu, Amanda Day, Nancy Wong, Mianmian Yin, Andres Canela, Haiqing Fu, Christophe Redon, Steven C. Pruitt, Yan Jaszczyszyn, Mirit I. Aladjem, Peter D. Aplan, Olivier Hyrien, André Nussenzweig Cell VOLUME 174, ISSUE 5, P1127-1142.E19, AUGUST 23, 2018 https://www.cell.com/cell/fulltext/S0092-8674(18)30905-X

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Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes Sara Rodriguez-Acebes, Silvana Mourón and Juan Méndez The Journal of Biological Chemistry293, 12855-12861.

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An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea Mengmeng Sun Xu Feng Zhenzhen Liu Wenyuan Han Yun Xiang Liang Qunxin She Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages 6697–6711

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An archaeal primase functions as a nanoscale caliper to define primer length Jiangyu Yan, Sandro Holzer, Luca Pellegrini, and Stephen D. Bell PNAS June 26, 2018. 115 (26) 6697-6702

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Conformational control and DNA-binding mechanism of the metazoan origin recognition complex Franziska Bleichert, Alexander Leitner, Ruedi Aebersold, Michael R. Botchan, and James M. Berger PNAS June 26, 2018. 115 (26) E5906-E5915

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Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks Kathrin S Heinz Corella S Casas-Delucchi Timea Török Dusan CmarkoAlexander Rapp Ivan Raska M Cristina Cardoso Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 6112–6128,

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Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Jithesh Kottur Deepak T Nair Nucleic Acids Research, Volume 46, Issue 12, 6 July 2018, Pages 5875–5885,

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Structure of the origin recognition complex bound to DNA replication origin Ningning Li, Wai Hei Lam, Yuanliang Zhai, Jiaxuan Cheng, Erchao Cheng, Yongqian Zhao, Ning Gao & Bik-Kwoon Tye Nature volume 559, pages217–222 (2018)

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High speed of fork progression induces DNA replication stress and genomic instability Apolinar Maya-Mendoza, Pavel Moudry, Joanna Maria Merchut-Maya, MyungHee Lee, Robert Strauss & Jiri Bartek Naturevolume 559, pages279–284 (2018)

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Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae Norah Owiti, Shanqiao Wei,Ashok S. Bhagwat,Nayun Kim PLoS Genet 14(7): e1007516.

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The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin Sang-Min Jang, Ya Zhang, Koichi Utani, Haiqing Fu, Christophe E. Redon, Anna B. Marks, Owen K. Smith, Catherine J. Redmond, Adrian M. Baris, Danielle A. Tulchinsky & Mirit I. Aladjem Nature Communications volume 9, Article number: 2782 (2018)

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Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells Nozomi Sugimoto Kazumitsu Maehara Kazumasa YoshidaYasuyuki Ohkawa Masatoshi Fujita Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages 6683–6696,

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High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing Alexandra M de Paz Thaddeus R Cybulski Adam H MarblestoneBradley M Zamft George M Church Edward S Boyden Konrad P KordingKeith E J Tyo Nucleic Acids Research, Volume 46, Issue 13, 27 July 2018, Pages e78,

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Shelterin promotes tethering of late replication origins to telomeres for replication‐timing control Shiho Ogawa, Sayuri Kido, Tetsuya Handa, Hidesato Ogawa, Haruhiko Asakawa, Tatsuro S Takahashi, Takuro Nakagawa, Yasushi Hiraoka, Hisao Masukata The EMBO Journal (2018) 37: e98997

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The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion Miroslav P Ivanov, Rene Ladurner, Ina Poser, RebeccaBeveridge, Evelyn Rampler, Otto Hudecz, MariaNovatchkova, Jean‐Karim Hériché, Gordana Wutz, Petravan der Lelij, Emanuel Kreidl, James RA Hutchins, HeinzAxelsson‐Ekker, Jan Ellenberg, Anthony A Hyman, KarlMechtler, Jan‐Michael Peters The EMBO Journal (2018) 37: e97150

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Endoreplication: The Good, the Bad, and the Ugly Zhiqiang Shu, Sarayu Row, Wu-Min Deng Trends in Cell Biology Volume 28, Issue 6, p465–474, June 2018

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Replication timing and nuclear structure HaiqingFu, AdrianBaris and Mirit Aladjem Current Opinion in Cell Biology Volume 52, June 2018, Pages 43-50

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The Initial Response of a Eukaryotic Replisome to DNA Damage Martin R.G. Taylor, Joseph T.P. Yeeles Molecular Cell Volume 70, Issue 6, p1067–1080.e12, 21 June 2018

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Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins Timothy A. Hoggard,FuJung Chang,Kelsey Rae Perry,Sandya Subramanian,Jessica Kenworthy,Julie Chueng,Erika Shor,Edel M. Hyland,Jef D. Boeke,Michael Weinreich ,Catherine A. Fox PLoS Genet 14(5): e1007418

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Challenges to DNA replication in hypoxic conditions Natalie Ng , Karin Purshouse, Iosifina P. Foskolou, Monica M. Olcina, Ester M. Hammond Febs J Volume285, Issue9 May 2018 Pages 1563-1571

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Muscle tensions merge to cause a DNA replication crisis Daniel Brayson, Chin Yee Ho, Catherine M. Shanahan JCB Home » 2018 Archive » 4 June » 217 (6): 1891

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Mechanotransduction via the LINC complex regulates DNA replication in myonuclei Shuoshuo Wang,Elizabeth Stoops,Unnikannan CP, Barak Markus,Adriana Reuveny,Elly Ordan,Talila Volk JCB Home » 2018 Archive » 4 June » 217 (6): 2005

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MCM interference during licensing of DNA replication in Xenopus egg extracts-Possible Role of a C-terminal region of MCM3- Satoru Mimura, Yumiko Kubota & Haruhiko Takisawa cell cycle 17 492-505

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Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation Tingjun Lei, Peixuan Zhang, Xudong Zhang, Xue Xiao, Jingli Zhang, Tong Qiu, Qian Dai, Yujun Zhang, Ling Min, Qian Li, Rutie Yin, Ping Ding, Ni Li, Yi Qu, Dezhi Mu, Jun Qin, Xiaofeng Zhu, Zhi-Xiong Xiao & Qintong Li Nature Communications volume 9,

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The Circadian Clock Sets the Time of DNA Replication Licensing to Regulate Growth in Arabidopsis Jorge Fung-Uceda, Kyounghee Lee, Pil Joon Seo, Stefanie Polyn, Lieven De Veylder, Paloma Mas Dev cell Volume 45, Issue 1, p101–113.e4, 9 April 2018

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RNase H eliminates R‐loops that disrupt DNA replication but is nonessential for efficient DSB repair Hongchang Zhao, Min Zhu, Oliver Limbo, Paul Russell EMBO reports (2018) 19, e45335

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A Mad2-Mediated Translational Regulatory Mechanism Promoting S-Phase Cyclin Synthesis Controls Origin Firing and Survival to Replication Stress Sophie Gay , Daniele Piccini, Christopher Bruhn, Sara Ricciardi, Paolo Soffientini, Walter Carotenuto, Stefano Biffo, Marco Foiani Mol cell Volume 70, Issue 4, p628–638.e5, 17 May 2018

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Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis Roberto Bellelli, Valerie Borel, Clare Logan, Jennifer Svendsen, Danielle E. Cox, Emma Nye, Kay Metcalfe, Susan M. O’Connell, Gordon Stamp, Helen R. Flynn, Ambrosius P. Snijders, François Lassailly, Andrew Jackson, Simon J. Boulton Mol cell Volume 70, Issue 4, p707–721.e7, 17 May 2018

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Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2 Aaron Mendez-Bermudez, Liudmyla Lototska, Serge Bauwens, Marie-Josèphe Giraud-Panis, Olivier Croce, Karine Jamet, Agurtzane Irizar, Macarena Mowinckel, Stephane Koundrioukoff, Nicolas Nottet, Genevieve Almouzni, Mare-Paule Teulade-Fichou, Michael Schertzer, Mylène Perderiset, Arturo Londoño-Vallejo, Michelle Debatisse, Eric Gilson, Jing Ye Mol Cell Volume 70, Issue 3, p449–461.e5, 3 May 2018

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Spatial separation between replisome‐ and template‐induced replication stress signalingThe EMBO Journal (2018) 37, e98369

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Lgr5+ intestinal stem cells reside in an unlicensed G1 phase Thomas D. Carroll,Ian P. Newton, Yu Chen, J. Julian Blow and Inke Näthke JCB 217 (5): 1667

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DNA replication licensing in stem cells: Gatekeeping the commitment to proliferation Hilary A. Coller J. Cell Biol. 2018 Vol. 217 No. 5 1563–1565

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Activity and fidelity of human DNA polymerase α depend on primer structure Andrey G. Baranovskiy, Vincent N. Duong, Nigar D. Babayeva, Yinbo Zhang, Youri I. Pavlov, Karen S. Anderson and Tahir H. Tahirov The Journal of Biological Chemistry293, 6824-6843

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SIRFing the replication fork: Assessing protein interactions with nascent DNA Dana Branzei and Michele Giannattasio J. Cell Biol. 2018 Vol. 217 No. 4 1177–1179

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SIRF: Quantitative in situ analysis of protein interactions at DNA replication forks Sunetra Roy, Jessica W. Luzwick, Katharina Schlacher J. Cell Biol. 2018 Vol. 217 No. 4 1521–1536

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The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism Huilin Li and Michael E. O'Donnell Bioessays Volume40, Issue3

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Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase Kohei Nukina, Akiyo Hayashi, Yasushi Shiomi, Kaoru Sugasawa, Motoaki Ohtsubo, Hideo Nishitani Genes to cels Volume23, Issue3 March 2018 Pages 200-213

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Pivotal roles of PCNA loading and unloading in heterochromatin function Ryan Janke, Grant A. King, Martin Kupiec and Jasper Rine PNAS February 27, 2018. 115 (9) E2030-E2039

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A mechanism for epigenetic control of DNA replication Courtney G. Sansam, Katarzyna Pietrzak, Blanka Majchrzycka, Maciej A. Kerlin, Jingrong Chen, Susannah Rankin and Christopher L. Sansam Genes & Dev. 2018. 32: 224-229

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The mechanism of eukaryotic CMG helicase activation Max E. Douglas, Ferdos Abid Ali, Alessandro Costa et al. Nature feb 2018

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Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress Morgane Macheret, Thanos D. Halazonetis Nature volume 555, pages 112–116

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Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae Marta A. Garbacz, Scott A. Lujan, Adam B. Burkholder, Phillip B. Cox, Qiuqin Wu, Zhi-Xiong Zhou, James E. Haber & Thomas A. Kunkel Nature Communicationsvolume 9, Article number: 858

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Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress Morgane Macheret, Thanos D. Halazonetis Nature Communications volume 9, Article number: 858

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PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry Angela Palmigiano,Francesco Santaniello, Aurora Cerutti,Dmitry Penkov,Divya Purushothaman, Ekta Makhija,Lucilla Luzi,Fabrizio d’Adda di Fagagna,Pier Giuseppe Pelicci,Viveswara Shivashankar,Gaetano Ivan Dellino &Francesco Blasi Scientific Reportsvolume 8, Article number: 3198

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Dormant origins and fork protection mechanisms rescue sister forks arrested by transcription Alessandra Brambati Luca Zardoni Yathish Jagadheesh Achar Daniele PicciniLorenzo Galanti Arianna Colosio Marco Foiani Giordano Liberi Nucleic Acids Research, Volume 46, Issue 3, 16 February 2018, Pages 1227–1239,

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Polymerase epsilon mutations and concomitant β2-microglobulin mutations in cancer Ioannis A.Voutsadaki GeneVolume 647, 20 March 2018, Pages 31-38

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Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei Takuya Okada,Gaku Okabe,Yon-Soo Tak,Satoru Mimura,Haruhiko Takisawa,Yumiko Kubota Genes to cells Volume 23, Pages 94–104

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The DNA Pol ϵ stimulatory activity of Mrc1 is modulated by phosphorylation Zhong-Xin Zhang, Jingjing Zhang, Qinhong Cao, Judith L. Campbell & Huiqiang Lou Cell Cycle Volume 17, 2018 Pages 64-72

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Replication of ribosomal DNA in Arabidopsis occurs both inside and outside the nucleolus during S phase progression Martina Dvořáčková, Berta Raposo, Petr Matula, Joerg Fuchs, Veit Schubert, Vratislav Peška, Bénédicte Desvoyes, Crisanto Gutierrez, Jiří Fajkus J Cell Sci 2018 131: jcs202416 doi: 10.1242/jcs.202416

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Single-cell replication profiling to measure stochastic variation in mammalian replication timing Vishnu Dileep & David M. Gilbert Nature Communications volume 9, Article number: 427

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The ring-shaped hexameric helicases that function at DNA replication forks Michael E. O’Donnell & Huilin Li Nature Structural & Molecular Biologyvolume 25, pages122–130 (2018)

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L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing Emily J. Platt, Leslie Smith, Mathew J. Thayer JCB 217 (2): 541

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Replication timing kept in LINE Rachel J. O’Neill, and Michael J. O’Neil J. Cell Biol. Vol. 217 No. 2 441–443

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Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe Pol Margalef Panagiotis Kotsantis, Valerie Borel, Roberto Bellelli, Stephanie Panier, Simon J. Boulton Volume 172, Issue 3, p439–453.e14, 25 January 2018

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Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing Dingqiang Fang,Armelle Lengronne, Di Shi, Romain Forey, Magdalena Skrzypczak, Krzysztof Ginalski, Changhui Yan, Xiaoke Wang, Qinhong Cao, Philippe Pasero and Huiqiang Lou Genes & Dev. 2017. 31: 2405-2415

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Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites Xiao P. Peng ,Shelly Lim ,Shibai Li,Lisette Marjavaara,Andrei Chabes,Xiaolan Zhao PLoS Genet 14(1): e1007129

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Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex Ewa Kowalska Filip Bartnicki Ryo Fujisawa Piotr Bonarek Paweł HermanowiczToshiki Tsurimoto Klaudia Muszyńska Wojciech Strzalka Nucleic Acids Research, Volume 46, Issue 1, 9 January 2018, Pages 25–41,

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Separase prevents genomic instability by controlling replication fork speed Francesco Cucco Elisa Palumbo Serena Camerini Barbara D’AlessioValentina Quarantotti Maria Luisa Casella Ilaria Maria Rizzo Dubravka CukrovDomenico Delia Antonella Russo Marco Crescenzi Antonio Musio Nucleic Acids Research, Volume 46, Issue 1, 9 January 2018, Pages 267–278,

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Replication origin–flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence Megan D. Warner, Ishara F. Azmi,Sukhyun Kang,Yanding Zhao and Stephen P. Bell December 29, 2017 The Journal of Biological Chemistry292, 21417-21430.

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Replication origin–flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence Megan D. Warner, Ishara F. Azmi, Sukhyun Kang, Yanding Zhao and Stephen P. Bell The Journal of Biological Chemistry292, 21417-21430.

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Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity Molly C. Kottemann, Brooke A. Conti, Francis P. Lach, Agata Smogorzewska Mol cell Volume 69, Issue 1, p24–35.e5, 4 January 2018

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Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions Jeongkyu Kim, David Sturgill, Robin Sebastian,Simran Khurana, Andy D. Tran, Garrett B. Edwards, Alex Kruswick, Sandra Burkett,Eri K. Hosogane, William W.Hannon, Urbain Weyemi, William M. Bonner, Karolin Luger, Philipp Oberdoerffer Mol Cell Volume 69, Issue 1, p36–47.e7, 4 January 2018

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Programming asynchronous replication in stem cells Hagit Masika, Marganit Farago, Merav Hecht, Reba Condiotti, Kirill Makedonski, Yosef Buganim, Tal Burstyn-Cohen, Yehudit Bergman& Howard Cedar Nature Structural & Molecular Biology 24, 1132–1138 (2017)