24 December 2022

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Human DNA polymerase α has a strong mutagenic potential at the initial steps of DNA synthesis Alisa E Lisova, Andrey G Baranovskiy, Lucia M Morstadt, Nigar D Babayeva, Tahir H Tahirov Nucleic Acids Research, Volume 50, Issue 21, 28 November 2022, Pages 12266–12273,

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New insights into DNA polymerase mechanisms provided by time-lapse crystallography Tyler M.Weaver, M. Todd Washington, Bret D.Freudenthal Current Opinion in Structural Biology Volume 77, December 2022, 102465

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Pold4 is dispensable for mouse development, DNA replication and DNA repair XuepingGu, Qinjin Dai, PengDu, Ning Li, Jiahui Li, Simiao Zeng, Shuyi Peng, Shengjun Tang, Lei Wang, Zhongcheng Zhou Gene Volume 851, 30 January 2023, 147029

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Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation Martin Meagher, Alexander Myasnikov, and Eric J. Enemark Int. J. Mol. Sci. 2022, 23(23), 14678;

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Global landscape of replicative DNA polymerase usage in the human genome Eri Koyanagi, Yoko Kakimoto, Tamiko Minamisawa, Fumiya Yoshifuji, Toyoaki Natsume, Atsushi Higashitani, Tomoo Ogi, Antony M. Carr, Masato T. Kanemaki & Yasukazu Daigaku Nature Communications volume 13, Article number: 7221 (2022)

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The non-catalytic role of DNA polymerase epsilon in replication initiation in human cells Sameera Vipat, Dipika Gupta, Sagun Jonchhe, Hele Anderspuk, Eli Rothenberg & Tatiana N. Moiseeva Nature Communications volume 13, Article number: 7099 (2022)

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Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions Karl-Uwe Reusswig, Julia Bittmann, Martina Peritore, Mathilde Courtes, Benjamin Pardo, Michael Wierer, Matthias Mann & Boris Pfander Nature Communications volume 13, Article number: 7014 (2022)

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Trypanosoma brucei Mitochondrial DNA Polymerase POLIB Contains a Novel Polymerase Domain Insertion That Confers Dominant Exonuclease Activity Stephanie B. Delzell, Scott W. Nelson, Matthew P. Frost, and Michele M. Klingbeil* Biochemistry 23, 2751–2765 November 18, 2022

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Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics Vlad-Stefan Raducanu, Muhammad Tehseen, Amani Al-Amodi, Luay I. Joudeh, Alfredo De Biasio & Samir M. Hamdan Nature Communications volume 13, Article number: 6973 (2022)

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Cell division drives DNA methylation loss in late-replicating domains in primary human cells Jamie L. Endicott, Paula A. Nolte, Hui Shen & Peter W. Laird Nature Communications volume 13, Article number: 6659 (2022)

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Unexpected new insights into DNA clamp loaders Huilin Li, Mike O'Donnell, Brian Kelch Bioessays Volume44, Issue11 November 2022

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DNA replication timing: Biochemical mechanisms and biological significance Nicholas Rhind Bioassays Volume44, Issue11 November 2022

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Replicon hypothesis revisited Hisao Masai Biochemical and Biophysical Research Communications Volume 633, 10 December 2022, Pages 77-80

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Replicon-seq: seeing is believing Cristian Polo Rivera Tom D. Deegan Trends in Genetics VOLUME 38, ISSUE 10, P987-988,

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Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L Cuige Zhu, Mari Iwase, Ziqian Li, Faliang Wang, Annabel Quinet, Alessandro Vindigni & Jieya Shao Nature Communications volume 13, Article number: 6531 (2022)

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Global early replication disrupts gene expression and chromatin conformation in a single cell cycle Miguel M. Santos, Mark C. Johnson, Lukáš Fiedler & Philip Zegerman Genome Biology volume 23, Article number: 217 (2022)

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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability Michael B. Heskett, Athanasios E. Vouzas, Leslie G. Smith, Phillip A. Yates, Christopher Boniface, Eric E. Bouhassira, Paul T. Spellman, David M. Gilbert & Mathew J. Thayer Nature Communications volume 13, Article number: 6301 (2022)

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DNA polymerase epsilon binds histone H3.1-H4 and recruits MORC1 to mediate meiotic heterochromatin condensation Cong Wang, Jiyue Huang, Yingping Li, Jun Zhang, Chengpeng He, Tianyang Li, Danhua Jiang, Aiwu Dong, Hong Ma, Gregory P. Copenhaver, and Yingxiang Wang PNAS 119 (43) e2213540119

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Origin recognition complex harbors an intrinsic nucleosome remodeling activity Sai Li, Michael R. Wasserman, Olga Yurieva, Lu Bai, Michael E. O’Donnell, and Shixin Liu PNAS 119 (42) e2211568119

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Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes Hana Polasek-Sedlackova, Thomas C. R. Miller, Jana Krejci, Maj-Britt Rask & Jiri Lukas Nature Communications volume 13, Article number: 6090 (2022)

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DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis Cong Wang, Jiyue Huang, Jun Zhang, Yue Yu, Gregory P. Copenhaver, Chenjiang You, and Yingxiang Wang PNAS 119 (41) e2208441119

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Rpd3 regulates single-copy origins independently of the rDNA array by opposing Fkh1-mediated origin stimulation Yiwei He, Meghan V. Petrie, Haiyang Zhang, Jared M. Peace, and Oscar M. Aparicio PNAS 119 (40) e2212134119

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ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress Xingxuan Wu, Shibin Xu, Peipei Wang,Zhao-Qi Wang, Hongxiang Chen, Xingzhi Xu , and Bin Peng PNAS 119 (40) e2203783119

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The consequences of differential origin licensing dynamics in distinct chromatin environments Liu Mei, Katarzyna M Kedziora, Eun-Ah Song, Jeremy E Purvis, Jeanette Gowen Cook Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9601–9620,

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Tracking of progressing human DNA polymerase δ holoenzymes reveals distributions of DNA lesion bypass activities Rachel L Dannenberg, Joseph A Cardina, Kara G Pytko, Mark Hedglin Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9893–9908,

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Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells Yann Benureau, Caroline Pouvelle, Pauline Dupaigne, Sonia Baconnais, Eliana Moreira Tavares, Gerard Mazón, Emmanuelle Despras, Eric Le Cam, Patricia L Kannouche Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9909–9929,

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3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells Karolina Jodkowska, Vera Pancaldi, Maria Rigau, Ricardo Almeida, José M Fernández-Justel, Osvaldo Graña-Castro, Sara Rodríguez-Acebes, Miriam Rubio-Camarillo, Enrique Carrillo-de Santa Pau, David Pisano Fátima Al-Shahrour, Alfonso Valencia, María Gómez, Juan Méndez Nucleic Acids Research, Volume 50, Issue 21, 28 November 2022, Pages 12149–12165,

22 September 2022

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Site-specific MCM sumoylation prevents genome rearrangements by controlling origin-bound MCM Yun Quan, Qian-yi Zhang, Ann L. Zhou, Yuhao Wang, Jiaxi Cai, Yong-qi Gao, Huilin Zhou PLoS Genet 18(6): e1010275.

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Telomere‐to‐telomere human DNA replication timing profiles Dashiell J. Massey & Amnon Koren Sci rep (2022) 12:9560

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Genome-wide mapping of individual replication fork velocities using nanopore sequencing Bertrand Theulot, Laurent Lacroix, Jean-Michel Arbona, Gael A. Millot, Etienne Jean, Corinne Cruaud, Jade Pellet, Florence Proux, Magali Hennion, Stefan Engelen, Arnaud Lemainque, Benjamin Audit, Olivier Hyrien & Benoît Le Tallec NATURE COMMUNICATIONS | (2022)13:3295

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Cohesin-mediated loop anchors confine the locations of human replication origins Daniel J. Emerson, Peiyao A. Zhao, Ashley L. Cook, R. Jordan Barnett,Kyle N. Klein, Dalila Saulebekova, Chunmin Ge, Linda Zhou, Zoltan Simandi, Miriam K. Minsk, Katelyn R. Titus, Weitao Wang, Wanfeng Gong, Di Zhang, Liyan Yang, Sergey V. Venev, Johan H. Gibcus, Hongbo Yang, Takayo Sasaki, Masato T. Kanemaki, Feng Yue, Job Dekker, Chun-Long Chen, David M. Gilbert & Jennifer E. Phillips-Cremins Nature | Vol606 | 23June2022

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Orc6 is a component of the replication fork and enables efficient mismatch repair Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Lyudmila Y. Kadyrova, You Jin Song, Qinyu Hao, Jaba Mitra, Rosaline Y. C. Hsu, Mariam K. Arif, Sneha Adusumilli, Ting-Wei Liao, Taekjip Ha, Farid A. Kadyrov, Kannanganattu V. Prasanth, and Supriya G. Prasanth PNAS May 27, 2022 119 (22) e2121406119

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HIRA-dependent boundaries between H3 variants shape early replication in mammals Alberto Gatto, Audrey Forest, Jean-Pierre Quivy and Geneviève Almouzni mol cell VOLUME 82, ISSUE 10, P1909-1923.E5,

19 September 2022

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Mechanism of replication origin melting nucleated by CMG helicase assembly Jacob S. Lewis, Marta H. Gross, Joana Sousa, Sarah S. Henrikus, Julia F. Greiwe, Andrea Nans, John F. X. Diffley & Alessandro Costa Nature volume 606, pages 1007–1014 (2022)

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DNA Replication proteins in primary microcephaly syndromes Melanie Tingler, Melanie Philipp, Martin D. Burkhalter Biology of the Cell Volume114, Issue June 2022 Pages 143-159

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Insight into RNA–DNA primer length counting by human primosome Andrey G Baranovskiy, Alisa E Lisova, Lucia M Morstadt, Nigar D Babayeva, Tahir H Tahirov Nucleic Acids Research, Volume 50, Issue 11, 24 June 2022, Pages 6264–6270,

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Structures of the human CST-Polα–primase complex bound to telomere templates Qixiang He, Xiuhua Lin, Bianca L. Chavez, Sourav Agrawal, Benjamin L. Lusk & Ci Ji Lim Nature volume 608, pages 826–832 (2022)

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Reconstitution of a telomeric replicon organized by CST Arthur J. Zaug, Karen J. Goodrich, Jessica J. Song, Ashley E. Sullivan & Thomas R. Cech Nature volume 608, pages 819–825 (2022)

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Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity Xiaoxiao Ma, Nadeem Riaz, Robert M. Samstein, Mark Lee, Vladimir Makarov, Cristina Valero, Diego Chowell, Fengshen Kuo, Douglas Hoen, Conall W. R. Fitzgerald, Hui Jiang, Jonathan Alektiar, Tyler J. Alban, Ivan Juric, Prerana Bangalore Parthasarathy, Yu Zhao, Erich Y. Sabio, Richa Verma, Raghvendra M. Srivastava, Lynda Vuong, Wei Yang, Xiao Zhang, Jingming Wang, Lawrence K. Chu, Stephen L. Wang, Daniel W. Kelly, Xin Pei, Jiapeng Chen, Rona Yaeger, Dmitriy Zamarin, Ahmet Zehir, Mithat Gönen, Luc G. T. Morris & Timothy A. Chan Nature Genetics volume 54, pages 996–1012 (2022)

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Mutations in DNA polymerase δ subunit 1 co-segregate with CMD2-type resistance to Cassava Mosaic Geminiviruses Yi-Wen Lim, Ben N. Mansfeld, Pascal Schläpfer, Kerrigan B. Gilbert, Narayanan N. Narayanan, Weihong Qi, Qi Wang, Zhenhui Zhong, Adam Boyher, Jackson Gehan, Getu Beyene, Zuh-Jyh Daniel Lin, Williams Esuma, Suhua Feng, Christelle Chanez, Nadine Eggenberger, Gerald Adiga, Titus Alicai, Steven E. Jacobsen, Nigel J. Taylor, Wilhelm Gruissem & Rebecca S. Bart Nature Communications volume 13, Article number: 3933 (2022)

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Filling in the blanks: how the C-strand catches up to the G-strand at replicating telomeres using CST Conner L. Olson, Alexandra T. Barbour & Deborah S. Wuttke Nature Structural & Molecular Biology volume 29, pages 730–733 (2022)

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Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ variants at low dNTP levels Stephanie R Barbari, Annette K Beach, Joel G Markgren, Vimal Parkash, Elizabeth A Moore, Erik Johansson, Polina V Shcherbakova Nucleic Acids Research, Volume 50, Issue 14, 12 August 2022, Pages 8023–8040,

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Cryo-EM structure of the human CST–Polα/primase complex in a recruitment state Sarah W. Cai, John C. Zinder, Vladimir Svetlov, Martin W. Bush, Evgeny Nudler, Thomas Walz & Titia de Lange Nature Structural & Molecular Biology volume 29, pages 813–819 (2022)

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Nucleosome-directed replication origin licensing independent of a consensus DNA sequence Sai Li, Michael R. Wasserman, Olga Yurieva, Lu Bai, Michael E. O’Donnell & Shixin Liu Nature Communications volume 13, Article number: 4947 (2022)

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Yeast ORC sumoylation status fine-tunes origin licensing Gemma Regan-Mochrie, Timothy Hoggard, Nikhil Bhagwat, Gerard Lynch, Neil Hunter, Dirk Remus, Catherine A. Fox and Xiaolan Zhao Genes & Dev. 2022. 36: 807-821

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Adaptive exchange sustains cullin–RING ubiquitin ligase networks and proper licensing of DNA replication Yaru Zhang, Marco Jost, Ryan A. Pak, Daniel Lu, Jing Li, Brett Lomenick, Spiros D. Garbis, Chi-Ming Li, Jonathan S. Weissman, James Russell Lipford, and Raymond J. Deshaies PNAS 119 (36) e2205608119

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The DNA replication protein Orc1 from the yeast Torulaspora delbrueckii is required for heterochromatin formation but not as a silencer-binding protein Haniam Maria, Laura N Rusche Genetics, Volume 222, Issue 1, September 2022, iyac110,

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Keeping the strands together: Rad53 regulation of fork symmetry promotes replication stability Zohreh Kianfard, Sarah A. Sabatinos Volume44, Issue9 September 2022 2200141

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Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context Toshihiro Matsukawa, Mianmian Yin, Timour Baslan, Yang Jo Chung, Dengchao Cao, Ryan Bertoli, Yuelin J. Zhu, Robert L. Walker, Amy Freeland, Erik Knudsen, Scott W. Lowe, Paul S. Meltzer, Peter D. Aplan Faseb J September 2022 e22430

20 May 2022

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Fast and efficient DNA replication with purified human proteins Yasemin Baris, Martin R. G. Taylor, Valentina Aria & Joseph T. P. Yeeles Nature 18 May 2022

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MCM complexes are barriers that restrict cohesin-mediated loop extrusion Bart J. H. Dequeker, Matthias J. Scherr, Hugo B. Brandão, Johanna Gassler, Sean Powell, Imre Gaspar, Ilya M. Flyamer, Aleksandar Lalic, Wen Tang, Roman Stocsits, Iain F. Davidson, Jan-Michael Peters, Karl E. Duderstadt, Leonid A. Mirny & Kikuë Tachibana Nature (2022) 18/5

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Kronos scRT: a uniform framework for single-cell replication timing analysis Stefano Gnan, Joseph M. Josephides, Xia Wu, Manuela Spagnuolo, Dalila Saulebekova, Mylène Bohec, Marie Dumont, Laura G. Baudrin, Daniele Fachinetti, Sylvain Baulande & Chun-Long Chen Nature Communications volume 13, Article number: 2329 (2022)

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High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control Dashiell J. Massey & Amnon Koren Nature Communications volume 13, Article number: 2402

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CDC7-independent G1/S transition revealed by targeted protein degradation Jan M. Suski, Nalin Ratnayeke, Marcin Braun, Tian Zhang, Vladislav Strmiska, Wojciech Michowski, Geylani Can, Antoine Simoneau, Konrad Snioch, Mikolaj Cup, Caitlin M. Sullivan, Xiaoji Wu, Joanna Nowacka, Timothy B. Branigan, Lindsey R. Pack, James A. DeCaprio, Yan Geng, Lee Zou, Steven P. Gygi, Johannes C. Walter, Tobias Meyer & Piotr Sicinski Nature volume 605, pages 357–365 (2022)

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Molecular basis for the initiation of DNA primer synthesis Arthur W. H. Li, Katerina Zabrady, Lewis J. Bainbridge, Matej Zabrady, Sehr Naseem-Khan, Madison B. Berger, Peter Kolesar, G. Andrés Cisneros & Aidan J. Doherty Nature (2022)04 May 2022

3 May 2022

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DNA replication fork speed underlies cell fate changes and promotes reprogramming Tsunetoshi Nakatani, Jiangwei Lin, Fei Ji, Andreas Ettinger, Julien Pontabry, Mikiko Tokoro, Luis Altamirano-Pacheco, Jonathan Fiorentino, Elmir Mahammadov, Yu Hatano, Capucine Van Rechem, Damayanti Chakraborty, Elias R. Ruiz-Morales, Paola Y. Arguello Pascualli, Antonio Scialdone, Kazuo Yamagata, Johnathan R. Whetstine, Ruslan I. Sadreyev & Maria-Elena Torres-Padilla Nature Genetics volume 54, pages 318–327 (2022)

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Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase Jiaxuan Cheng, Ningning Li, Yunjing Huo, Shangyu Dang, Bik-Kwoon Tye, Ning Gao & Yuanliang Zhai Nature Communications volume 13, Article number: 1396 (2022)

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Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome Keisuke Oki, Mariko Nagata, Takeshi Yamagami, Tomoyuki Numata, Sonoko Ishino, Takuji Oyama, Yoshizumi Ishino Nucleic Acids Research, Volume 50, Issue 7, 22 April 2022, Pages 3601–3615,

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Single-molecule mapping of replisome progression Clémence Claussin, Jacob Vazquez, Iestyn Whitehouse Mol cell Published:March 02, 2022

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Mapping replication forks, one replicon at a time Nicholas Rhind Mol Cell VOLUME 82, ISSUE 7, P1246-1248, APRIL 07, 2022

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Stable G-quadruplex DNA structures promote replication-dependent genome instability S. Dean Rider Jr.,Rujuta Yashodhan Gadgi, David C. Hitch, Resha Shrestha, Kazuo Shin-ya, Michael Leffak JBC in press

7 March 2022

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The inner workings of replisome-dependent control of DNA damage tolerance Tianpeng Zhang and Roger A. Greenberg Genes & Dev. 2022. 36: 103-105

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Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance Valeria Dolce, Sabrina Dusi, Michele Giannattasio, Chinnu Rose Joseph, Marco Fumasoni and Dana Branzei Genes & Dev. 2022. 36: 167-179

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A DNA replication-independent function of pre-replication complex genes during cell invasion in C. elegans. Lattmann E, Deng T, Walser M, Widmer P, Rexha-Lambert C, Prasad V, et al. PLoS Biol 20(2): e3001317.

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Prereplication complex proteins get caught moonlighting. Coller HA PLoS Biol 20(2): e3001549.

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The fork protection complex recruits FACT to reorganize nucleosomes during replication Barbara Safaric, Erika Chacin, Matthias J Scherr, Lional Rajappa, Christian Gebhardt, Christoph F Kurat, Thorben Cordes, Karl E Duderstadt Nucleic Acids Research, Volume 50, Issue 3, 22 February 2022, Pages 1317–1334,

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A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6 Jan Marten Schmidt, Ran Yang, Ashish Kumar, Olivia Hunker, Jan Seebacher & Franziska Bleichert Nature Communications volume 13, Article number: 1059 (2022)

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Genomic patterns of transcription–replication interactions in mouse primary B cells Commodore P St Germain, Hongchang Zhao, Vrishti Sinha, Lionel A Sanz, Frédéric Chédin, Jacqueline H Barlow Nucleic Acids Research, Volume 50, Issue 4, 28 February 2022, Pages 2051–2073,

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Transcription-replication coordination revealed in single live cells Ioannis Tsirkas, Daniel Dovrat, Manikandan Thangaraj, Ineke Brouwer, Amit Cohen, Zohar Paleiov, Michael M Meijler, Tineke Lenstra, Amir Aharoni Nucleic Acids Research, Volume 50, Issue 4, 28 February 2022, Pages 2143–2156,

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Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress Rebecca L. Kelly, Amelia M. Huehls, Annapoorna Venkatachalam, Catherine J. Huntoon, Yuichi J. Machida,Larry M. Karnitz JBC in press

21 February 2022

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Dbf4-Dependent Kinase: DDK-ated to post-initiation events in DNA replication Andrew Dolson, Safia Mahabub Sauty, Kholoud Shaban & Krassimir Yankulov Cell Cycle Volume 20, 2021 - Issue 22

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Preventing excess replication origin activation to ensure genome stability Bhushan L. Thakur, Anagh Ray, Christophe E. Redon,Mirit I. Aladjem TIGS | VOLUME 38, ISSUE 2, P169-181, FEBRUARY 01, 2022

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In silico reconstitution of DNA replication. Lessons from single-molecule imaging and cryo-tomography applied to single-particle cryo-EM Julia F.Greiwe, GiuliaZanetti, Thomas C.R.Mille, AlessandroCosta Current Opinion in Structural Biology Volume 72, February 2022, Pages 279-286

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The yeast Dbf4 Zn2+ finger domain suppresses single-stranded DNA at replication forks initiated from a subset of origins Jeff Bachant, Elizabeth A. Hoffman, Chris Caridi, Constance I. Nugent & Wenyi Feng Current Genetics (2022)

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Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint Lili Li, Jie Wang, Zijia Yang, Yiling Zhao, Hui Jiang, Luguang Jiang, Wenya Hou, Risheng Ye, Qun He, Martin Kupiec, Brian Luke, Qinhong Cao, Zhi Qi, Zhen Li, Huiqiang Lou The EMBO Journal (2022)41:e108290

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Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint Hovik Gasparayan, Chris Caridi, Jeff Julius, Wenyi Feng, Jeff Bachant & Constance I. Nugent Current Genetics (2022)

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A novel link between the DNA replication machinery and chromatin assembly J Cell Sci (2022) 135 (2): e135_e0202.

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SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication Caitlin Connolly,Saori Takahashi,Hisashi Miura,Ichiro Hiratani,Nick Gilbert,Anne D. Donaldson,Shin-Ichiro Hiraga J Cell Sci (2022) 135 (2): jcs258991.

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Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability Taha Mohamed, Madison B. Adolph, David Cortez JBC in press

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Proline-specific aminopeptidase P prevents replication-associated genome instability Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R. Brooks, R. Elwyn Isaac, Simon J. Boulton, Enrique Martinez-Perez PLoS Genet 18(1): e1010025.

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Stimulation of adaptive gene amplification by origin firing under replication fork constraint Alex J Whale, Michelle King, Ryan M Hull, Felix Krueger, Jonathan Houseley Nucleic Acids Research, Volume 50, Issue 2, 25 January 2022, Pages 915–936,

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Probing the mechanisms of two exonuclease domain mutators of DNA polymerase ϵ Joseph M Dahl, Natalie Thomas, Maxwell A Tracy, Brady L Hearn, Lalith Perera, Scott R Kennedy, Alan J Herr, Thomas A Kunkel Nucleic Acids Research, Volume 50, Issue 2, 25 January 2022,

24 January 2022

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How asymmetric DNA replication achieves symmetrical fidelity Zhi-Xiong Zhou, Scott A. Lujan, Adam B. Burkholder, Jordan St. Charles, Joseph Dahl, Corinne E. Farrell, Jessica S. Williams & Thomas A. Kunkel Nature Structural & Molecular Biology volume 28, pages 1020–1028 (2021)

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Blm helicase facilitates rapid replication of repetitive DNA sequences in early Drosophila development Jolee M Ruchert, Morgan M Brady, Susan McMahan, Karly J Lacey, Leigh C Latta, Jeff Sekelsky, Eric P Stoffregen Genetics, Volume 220, Issue 1, January 2022, iyab169

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Geminin is essential for DNA re-replication in the silk gland cells of silkworms Tai-HangLiu, Xiao-Long Dong, Peng Chen, QianZhang, Xiao-LinZhou, ChengLu, Min-HuiPan Experimental Cell Research Volume 410, Issue 1, 1 January 2022, 112951

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Water skating: How polymerase sliding clamps move on DNA Huilin Li, Fengwei Zheng, Mike O’Donnell Febs JournalVolume288, Issue24 December 2021 Pages 7256-7262

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CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism Nina Y. Yao, Dan Zhang, Olga Yurieva, and Michael E. O’Donnell PNAS January 25, 2022 119 (4) e2119580119

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Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley & Alessandro Costa Nature Structural & Molecular Biology volume 29, pages 10–20 (2022)