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Trypanosoma bruceiOrc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching Imaan Benmerzouga, Jeniffer Concepción-Acevedo, Hee-Sook Kim, Anthula V. Vandoros, George A. M. Cross, Michele M. Klingbeil and Bibo Li Molecular Microbiology Volume 87, Issue 1, pages 196–210, January 2013