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BRCA2 reversion mutation–independent resistance to PARP inhibition through impaired DNA prereplication complex function Kyrie Pappas, Matteo Ferrari, Perianne Smith, Subhiksha Nandakumar, Zahra Khan, Serina B. Young, Justin LaClair, Marco Vincenzo Russo, Emmet Huang-Hobbs, Nikolaus Schultz, Wassim Abida, Wouter Karthaus, Maria Jasin and Charles L. Sawyers PNAS June 3, 2025122 (23) e2426743122